Effects of Vitamin D on Fertility, Pregnancy and Polycystic Ovary Syndrome—A Review
Polycystic ovary syndrome (PCOS) is one of the most common endocrine reproductive disorders in women. Vitamin D deficiency is also quite common in this condition. The degree of vitamin D deficiency correlates with the severity of PCOS. Both male and female vitamin D levels play a role in fertility a...
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MDPI AG
2022-04-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/14/8/1649 |
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| author | Szabolcs Várbíró István Takács László Tűű Katalin Nas Réka Eszter Sziva Judit Réka Hetthéssy Marianna Török |
| author_facet | Szabolcs Várbíró István Takács László Tűű Katalin Nas Réka Eszter Sziva Judit Réka Hetthéssy Marianna Török |
| author_sort | Szabolcs Várbíró |
| collection | DOAJ |
| description | Polycystic ovary syndrome (PCOS) is one of the most common endocrine reproductive disorders in women. Vitamin D deficiency is also quite common in this condition. The degree of vitamin D deficiency correlates with the severity of PCOS. Both male and female vitamin D levels play a role in fertility and affect the outcomes of in vitro fertilization (IVF). Moreover, fertility and IVF indicators are improved by vitamin D not only in healthy women but in those diagnosed with PCOS. Both vitamin D deficiency and PCOS increase pregnancy-related complications. Vitamin D supplementation and optimal vitamin D levels decrease both maternal and fetal risk for complications and adverse events. Furthermore, vitamin D supplementation may ameliorate or even prevent pregnancy-related reversible bone loss in mothers. This review emphasizes the roles of vitamin D deficiency and vitamin D supplementation and their correlation with PCOS regarding reproductive health. |
| first_indexed | 2024-03-09T10:30:44Z |
| format | Article |
| id | doaj.art-0b9cd1c4c4f843ec941654aaf30e282e |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T10:30:44Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-0b9cd1c4c4f843ec941654aaf30e282e2023-12-01T21:17:31ZengMDPI AGNutrients2072-66432022-04-01148164910.3390/nu14081649Effects of Vitamin D on Fertility, Pregnancy and Polycystic Ovary Syndrome—A ReviewSzabolcs Várbíró0István Takács1László Tűű2Katalin Nas3Réka Eszter Sziva4Judit Réka Hetthéssy5Marianna Török6Department of Obstetrics and Gynecology, Semmelweis University, Üllői Street 78/a, 1082 Budapest, HungaryDepartment of Internal Medicine and Oncology, Semmelweis University, Sándor Korányi Street 2/a, 1098 Budapest, HungaryEndoCare Institute, Endocrinology Center, Bokor Street 17-21, 1037 Budapest, HungaryEndoCare Institute, Endocrinology Center, Bokor Street 17-21, 1037 Budapest, HungaryDepartment of Obstetrics and Gynecology, Semmelweis University, Üllői Street 78/a, 1082 Budapest, HungaryWorkgroup of Research Management, Doctoral School, Semmelweis University, Üllői Street 22, 1085 Budapest, HungaryDepartment of Obstetrics and Gynecology, Semmelweis University, Üllői Street 78/a, 1082 Budapest, HungaryPolycystic ovary syndrome (PCOS) is one of the most common endocrine reproductive disorders in women. Vitamin D deficiency is also quite common in this condition. The degree of vitamin D deficiency correlates with the severity of PCOS. Both male and female vitamin D levels play a role in fertility and affect the outcomes of in vitro fertilization (IVF). Moreover, fertility and IVF indicators are improved by vitamin D not only in healthy women but in those diagnosed with PCOS. Both vitamin D deficiency and PCOS increase pregnancy-related complications. Vitamin D supplementation and optimal vitamin D levels decrease both maternal and fetal risk for complications and adverse events. Furthermore, vitamin D supplementation may ameliorate or even prevent pregnancy-related reversible bone loss in mothers. This review emphasizes the roles of vitamin D deficiency and vitamin D supplementation and their correlation with PCOS regarding reproductive health.https://www.mdpi.com/2072-6643/14/8/1649polycystic ovary syndromePCOSvitamin Dvitamin D deficiencyvitamin D supplementationfemale fertility |
| spellingShingle | Szabolcs Várbíró István Takács László Tűű Katalin Nas Réka Eszter Sziva Judit Réka Hetthéssy Marianna Török Effects of Vitamin D on Fertility, Pregnancy and Polycystic Ovary Syndrome—A Review Nutrients polycystic ovary syndrome PCOS vitamin D vitamin D deficiency vitamin D supplementation female fertility |
| title | Effects of Vitamin D on Fertility, Pregnancy and Polycystic Ovary Syndrome—A Review |
| title_full | Effects of Vitamin D on Fertility, Pregnancy and Polycystic Ovary Syndrome—A Review |
| title_fullStr | Effects of Vitamin D on Fertility, Pregnancy and Polycystic Ovary Syndrome—A Review |
| title_full_unstemmed | Effects of Vitamin D on Fertility, Pregnancy and Polycystic Ovary Syndrome—A Review |
| title_short | Effects of Vitamin D on Fertility, Pregnancy and Polycystic Ovary Syndrome—A Review |
| title_sort | effects of vitamin d on fertility pregnancy and polycystic ovary syndrome a review |
| topic | polycystic ovary syndrome PCOS vitamin D vitamin D deficiency vitamin D supplementation female fertility |
| url | https://www.mdpi.com/2072-6643/14/8/1649 |
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