Shed EBA-175 mediates red blood cell clustering that enhances malaria parasite growth and enables immune evasion
Erythrocyte Binding Antigen of 175 kDa (EBA-175) has a well-defined role in binding to glycophorin A (GpA) during Plasmodium falciparum invasion of erythrocytes. However, EBA-175 is shed post invasion and a role for this shed protein has not been defined. We show that EBA-175 shed from parasites pro...
Main Authors: | May M Paing, Nichole D Salinas, Yvonne Adams, Anna Oksman, Anja TR Jensen, Daniel E Goldberg, Niraj H Tolia |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/43224 |
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