Retrospective analysis of therapeutic response obtained with enteral and parenteral iron in adults with iron deficiency anaemia

Background: Few studies compare the therapeutic efficacy of different iron deficiency anaemia treatments. Aim: Evaluate the therapeutic response of the most common iron preparations. Material and methods: Retrospective, observational-analytical study based on medical records from the Haematology Dep...

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Main Authors: G. Barragán-Ibañez, A. Santoyo-Sánchez, J. Collazo-Jaloma, C.O. Ramos-Peñafiel
Format: Article
Language:English
Published: Permanyer 2015-07-01
Series:Revista Médica del Hospital General de México
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0185106315000487
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author G. Barragán-Ibañez
A. Santoyo-Sánchez
J. Collazo-Jaloma
C.O. Ramos-Peñafiel
author_facet G. Barragán-Ibañez
A. Santoyo-Sánchez
J. Collazo-Jaloma
C.O. Ramos-Peñafiel
author_sort G. Barragán-Ibañez
collection DOAJ
description Background: Few studies compare the therapeutic efficacy of different iron deficiency anaemia treatments. Aim: Evaluate the therapeutic response of the most common iron preparations. Material and methods: Retrospective, observational-analytical study based on medical records from the Haematology Department, conducted from March to October 2014, including 121 adults with ferropenic anaemia and 3-month follow-up. Patients with comorbidities or pregnancy were excluded. Results: 85.8% were women (n = 103) and 14% men (n = 17), with a mean age of 42 (16–83) years. Seventy patients (58.3%) started with oral administration; the rest received intravenous iron. Efficacy was similar among all the iron preparations, with no significant differences (p > 0.05). Iron sucrose was most effective in rapidly replenishing body iron stores. Conclusions: Despite comparable efficacy among treatments, ferrous fumarate had the lowest treatment failure and was the therapy of choice.
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spelling doaj.art-0ba202cfaa494afe81a14e5eb73f8ad82022-12-22T02:17:34ZengPermanyerRevista Médica del Hospital General de México0185-10632015-07-0178311211810.1016/j.hgmx.2015.08.005Retrospective analysis of therapeutic response obtained with enteral and parenteral iron in adults with iron deficiency anaemiaG. Barragán-Ibañez0A. Santoyo-Sánchez1J. Collazo-Jaloma2C.O. Ramos-Peñafiel3Servicio de Hematología, Hospital General de México “Dr. Eduardo Liceaga”, Mexico City, MexicoFacultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, MexicoServicio de Hematología, Hospital General de México “Dr. Eduardo Liceaga”, Mexico City, MexicoServicio de Hematología, Hospital General de México “Dr. Eduardo Liceaga”, Mexico City, MexicoBackground: Few studies compare the therapeutic efficacy of different iron deficiency anaemia treatments. Aim: Evaluate the therapeutic response of the most common iron preparations. Material and methods: Retrospective, observational-analytical study based on medical records from the Haematology Department, conducted from March to October 2014, including 121 adults with ferropenic anaemia and 3-month follow-up. Patients with comorbidities or pregnancy were excluded. Results: 85.8% were women (n = 103) and 14% men (n = 17), with a mean age of 42 (16–83) years. Seventy patients (58.3%) started with oral administration; the rest received intravenous iron. Efficacy was similar among all the iron preparations, with no significant differences (p > 0.05). Iron sucrose was most effective in rapidly replenishing body iron stores. Conclusions: Despite comparable efficacy among treatments, ferrous fumarate had the lowest treatment failure and was the therapy of choice.http://www.sciencedirect.com/science/article/pii/S0185106315000487Iron-deficiency anaemiaAdultFerric compoundsTreatment outcomeOral administration
spellingShingle G. Barragán-Ibañez
A. Santoyo-Sánchez
J. Collazo-Jaloma
C.O. Ramos-Peñafiel
Retrospective analysis of therapeutic response obtained with enteral and parenteral iron in adults with iron deficiency anaemia
Revista Médica del Hospital General de México
Iron-deficiency anaemia
Adult
Ferric compounds
Treatment outcome
Oral administration
title Retrospective analysis of therapeutic response obtained with enteral and parenteral iron in adults with iron deficiency anaemia
title_full Retrospective analysis of therapeutic response obtained with enteral and parenteral iron in adults with iron deficiency anaemia
title_fullStr Retrospective analysis of therapeutic response obtained with enteral and parenteral iron in adults with iron deficiency anaemia
title_full_unstemmed Retrospective analysis of therapeutic response obtained with enteral and parenteral iron in adults with iron deficiency anaemia
title_short Retrospective analysis of therapeutic response obtained with enteral and parenteral iron in adults with iron deficiency anaemia
title_sort retrospective analysis of therapeutic response obtained with enteral and parenteral iron in adults with iron deficiency anaemia
topic Iron-deficiency anaemia
Adult
Ferric compounds
Treatment outcome
Oral administration
url http://www.sciencedirect.com/science/article/pii/S0185106315000487
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AT jcollazojaloma retrospectiveanalysisoftherapeuticresponseobtainedwithenteralandparenteralironinadultswithirondeficiencyanaemia
AT coramospenafiel retrospectiveanalysisoftherapeuticresponseobtainedwithenteralandparenteralironinadultswithirondeficiencyanaemia