Retrospective analysis of therapeutic response obtained with enteral and parenteral iron in adults with iron deficiency anaemia
Background: Few studies compare the therapeutic efficacy of different iron deficiency anaemia treatments. Aim: Evaluate the therapeutic response of the most common iron preparations. Material and methods: Retrospective, observational-analytical study based on medical records from the Haematology Dep...
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2015-07-01
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Series: | Revista Médica del Hospital General de México |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S0185106315000487 |
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author | G. Barragán-Ibañez A. Santoyo-Sánchez J. Collazo-Jaloma C.O. Ramos-Peñafiel |
author_facet | G. Barragán-Ibañez A. Santoyo-Sánchez J. Collazo-Jaloma C.O. Ramos-Peñafiel |
author_sort | G. Barragán-Ibañez |
collection | DOAJ |
description | Background: Few studies compare the therapeutic efficacy of different iron deficiency anaemia treatments.
Aim: Evaluate the therapeutic response of the most common iron preparations.
Material and methods: Retrospective, observational-analytical study based on medical records from the Haematology Department, conducted from March to October 2014, including 121 adults with ferropenic anaemia and 3-month follow-up. Patients with comorbidities or pregnancy were excluded.
Results: 85.8% were women (n = 103) and 14% men (n = 17), with a mean age of 42 (16–83) years. Seventy patients (58.3%) started with oral administration; the rest received intravenous iron. Efficacy was similar among all the iron preparations, with no significant differences (p > 0.05). Iron sucrose was most effective in rapidly replenishing body iron stores.
Conclusions: Despite comparable efficacy among treatments, ferrous fumarate had the lowest treatment failure and was the therapy of choice. |
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format | Article |
id | doaj.art-0ba202cfaa494afe81a14e5eb73f8ad8 |
institution | Directory Open Access Journal |
issn | 0185-1063 |
language | English |
last_indexed | 2024-04-14T02:34:00Z |
publishDate | 2015-07-01 |
publisher | Permanyer |
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series | Revista Médica del Hospital General de México |
spelling | doaj.art-0ba202cfaa494afe81a14e5eb73f8ad82022-12-22T02:17:34ZengPermanyerRevista Médica del Hospital General de México0185-10632015-07-0178311211810.1016/j.hgmx.2015.08.005Retrospective analysis of therapeutic response obtained with enteral and parenteral iron in adults with iron deficiency anaemiaG. Barragán-Ibañez0A. Santoyo-Sánchez1J. Collazo-Jaloma2C.O. Ramos-Peñafiel3Servicio de Hematología, Hospital General de México “Dr. Eduardo Liceaga”, Mexico City, MexicoFacultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, MexicoServicio de Hematología, Hospital General de México “Dr. Eduardo Liceaga”, Mexico City, MexicoServicio de Hematología, Hospital General de México “Dr. Eduardo Liceaga”, Mexico City, MexicoBackground: Few studies compare the therapeutic efficacy of different iron deficiency anaemia treatments. Aim: Evaluate the therapeutic response of the most common iron preparations. Material and methods: Retrospective, observational-analytical study based on medical records from the Haematology Department, conducted from March to October 2014, including 121 adults with ferropenic anaemia and 3-month follow-up. Patients with comorbidities or pregnancy were excluded. Results: 85.8% were women (n = 103) and 14% men (n = 17), with a mean age of 42 (16–83) years. Seventy patients (58.3%) started with oral administration; the rest received intravenous iron. Efficacy was similar among all the iron preparations, with no significant differences (p > 0.05). Iron sucrose was most effective in rapidly replenishing body iron stores. Conclusions: Despite comparable efficacy among treatments, ferrous fumarate had the lowest treatment failure and was the therapy of choice.http://www.sciencedirect.com/science/article/pii/S0185106315000487Iron-deficiency anaemiaAdultFerric compoundsTreatment outcomeOral administration |
spellingShingle | G. Barragán-Ibañez A. Santoyo-Sánchez J. Collazo-Jaloma C.O. Ramos-Peñafiel Retrospective analysis of therapeutic response obtained with enteral and parenteral iron in adults with iron deficiency anaemia Revista Médica del Hospital General de México Iron-deficiency anaemia Adult Ferric compounds Treatment outcome Oral administration |
title | Retrospective analysis of therapeutic response obtained with enteral and parenteral iron in adults with iron deficiency anaemia |
title_full | Retrospective analysis of therapeutic response obtained with enteral and parenteral iron in adults with iron deficiency anaemia |
title_fullStr | Retrospective analysis of therapeutic response obtained with enteral and parenteral iron in adults with iron deficiency anaemia |
title_full_unstemmed | Retrospective analysis of therapeutic response obtained with enteral and parenteral iron in adults with iron deficiency anaemia |
title_short | Retrospective analysis of therapeutic response obtained with enteral and parenteral iron in adults with iron deficiency anaemia |
title_sort | retrospective analysis of therapeutic response obtained with enteral and parenteral iron in adults with iron deficiency anaemia |
topic | Iron-deficiency anaemia Adult Ferric compounds Treatment outcome Oral administration |
url | http://www.sciencedirect.com/science/article/pii/S0185106315000487 |
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