Suicide risk in comorbid bipolar disorder and obsessive-compulsive disorder: A systematic review
Introduction: The co-occurrence of bipolar disorder (BD) and obsessive-compulsive disorder (OCD) seemed to be a poor prognostic factor associated with greater disability, lower social and occupational functioning, poorer treatment response, and higher suicidal ideas and attempts compared to BD patie...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2019-01-01
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| Series: | Indian Journal of Psychological Medicine |
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| Online Access: | http://www.ijpm.info/article.asp?issn=0253-7176;year=2019;volume=41;issue=2;spage=133;epage=137;aulast=Amerio |
| _version_ | 1818583637008842752 |
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| author | Andrea Amerio |
| author_facet | Andrea Amerio |
| author_sort | Andrea Amerio |
| collection | DOAJ |
| description | Introduction: The co-occurrence of bipolar disorder (BD) and obsessive-compulsive disorder (OCD) seemed to be a poor prognostic factor associated with greater disability, lower social and occupational functioning, poorer treatment response, and higher suicidal ideas and attempts compared to BD patients. Materials and Methods: A systematic review was conducted on the risk of suicide in BD-OCD patients compared to BD patients. Relevant papers published through August 2018 were identified searching the electronic databases MEDLINE, EMBASE, PsycINFO, and the Cochrane Library. Results: In all cases, diagnoses were according to the standard Diagnostic and Statistical Manual criteria and were established using validated assessment scales. More than 80% of the selected studies presented higher rates of history of suicide attempts and lifetime depressive episodes in BD-OCD patients compared to non-comorbid patients. Conclusions: Osler's view that medicine should be a treatment of diseases, not of symptoms, is consistent with the approach of mood stabilization as the first objective in apparent BD-OCD patients, as opposed to immediate treatment with antidepressants. In line with that, especially in comorbid patients, lithium may be preferred because of its proven anti-suicidal effect. |
| first_indexed | 2024-12-16T08:08:26Z |
| format | Article |
| id | doaj.art-0ba4dc1ed77143219261c079df201542 |
| institution | Directory Open Access Journal |
| issn | 0253-7176 |
| language | English |
| last_indexed | 2024-12-16T08:08:26Z |
| publishDate | 2019-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Indian Journal of Psychological Medicine |
| spelling | doaj.art-0ba4dc1ed77143219261c079df2015422022-12-21T22:38:24ZengSAGE PublishingIndian Journal of Psychological Medicine0253-71762019-01-0141213313710.4103/IJPSYM.IJPSYM_367_18Suicide risk in comorbid bipolar disorder and obsessive-compulsive disorder: A systematic reviewAndrea AmerioIntroduction: The co-occurrence of bipolar disorder (BD) and obsessive-compulsive disorder (OCD) seemed to be a poor prognostic factor associated with greater disability, lower social and occupational functioning, poorer treatment response, and higher suicidal ideas and attempts compared to BD patients. Materials and Methods: A systematic review was conducted on the risk of suicide in BD-OCD patients compared to BD patients. Relevant papers published through August 2018 were identified searching the electronic databases MEDLINE, EMBASE, PsycINFO, and the Cochrane Library. Results: In all cases, diagnoses were according to the standard Diagnostic and Statistical Manual criteria and were established using validated assessment scales. More than 80% of the selected studies presented higher rates of history of suicide attempts and lifetime depressive episodes in BD-OCD patients compared to non-comorbid patients. Conclusions: Osler's view that medicine should be a treatment of diseases, not of symptoms, is consistent with the approach of mood stabilization as the first objective in apparent BD-OCD patients, as opposed to immediate treatment with antidepressants. In line with that, especially in comorbid patients, lithium may be preferred because of its proven anti-suicidal effect.http://www.ijpm.info/article.asp?issn=0253-7176;year=2019;volume=41;issue=2;spage=133;epage=137;aulast=AmerioBipolarcomorbidityobsessive-compulsivesuicide |
| spellingShingle | Andrea Amerio Suicide risk in comorbid bipolar disorder and obsessive-compulsive disorder: A systematic review Indian Journal of Psychological Medicine Bipolar comorbidity obsessive-compulsive suicide |
| title | Suicide risk in comorbid bipolar disorder and obsessive-compulsive disorder: A systematic review |
| title_full | Suicide risk in comorbid bipolar disorder and obsessive-compulsive disorder: A systematic review |
| title_fullStr | Suicide risk in comorbid bipolar disorder and obsessive-compulsive disorder: A systematic review |
| title_full_unstemmed | Suicide risk in comorbid bipolar disorder and obsessive-compulsive disorder: A systematic review |
| title_short | Suicide risk in comorbid bipolar disorder and obsessive-compulsive disorder: A systematic review |
| title_sort | suicide risk in comorbid bipolar disorder and obsessive compulsive disorder a systematic review |
| topic | Bipolar comorbidity obsessive-compulsive suicide |
| url | http://www.ijpm.info/article.asp?issn=0253-7176;year=2019;volume=41;issue=2;spage=133;epage=137;aulast=Amerio |
| work_keys_str_mv | AT andreaamerio suicideriskincomorbidbipolardisorderandobsessivecompulsivedisorderasystematicreview |