Testosterone Protects Against Severe Influenza by Reducing the Pro-Inflammatory Cytokine Response in the Murine Lung

Testosterone Protects Against Severe Influenza by Reducing the Pro-Inflammatory Cytokine Response in the Murine Lung

Influenza A virus pathogenesis may differ between men and women. The 2009 H1N1 influenza pandemic resulted in more documented hospitalizations in women compared to men. In this study, we analyzed the impact of male sex hormones on pandemic 2009 H1N1 influenza A virus disease outcome. In a murine inf...

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Bibliographic Details
Main Authors: Berfin Tuku, Stephanie Stanelle-Bertram, Julie Sellau, Sebastian Beck, Tian Bai, Nancy Mounogou Kouassi, Annette Preuß, Stefan Hoenow, Thomas Renné, Hanna Lotter, Gülsah Gabriel
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
influenza A virus
sex differences
testosterone
2009 H1N1
androgens
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00697/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00697/full

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