Physical activity enhances fecal lactobacilli in rats chronically drinking sweetened cola beverage
Overweight and obesity have been linked with increased intake of sugar-sweetened beverages. On the other hand, physical activity has been known to lead to weight loss. Therefore, we hypothesized that exercise might influence the Lactobacillus population in fecal microbiota as their changed abundance...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2022-06-01
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| Series: | Open Life Sciences |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/biol-2022-0070 |
| _version_ | 1828108219725119488 |
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| author | Marusakova Margareta Dudik Boris Hadova Katarina Kmecova Zuzana Kralova Eva Krenek Peter Bilkova Andrea Klimas Jan |
| author_facet | Marusakova Margareta Dudik Boris Hadova Katarina Kmecova Zuzana Kralova Eva Krenek Peter Bilkova Andrea Klimas Jan |
| author_sort | Marusakova Margareta |
| collection | DOAJ |
| description | Overweight and obesity have been linked with increased intake of sugar-sweetened beverages. On the other hand, physical activity has been known to lead to weight loss. Therefore, we hypothesized that exercise might influence the Lactobacillus population in fecal microbiota as their changed abundance is often associated with shifts in the physical activity and diet. In our experiment, Wistar rats were allocated into groups with normal feed or added sugar-sweetened beverages with or without access to a running wheel. Interestingly, only a combination of physical activity and sweetened beverage intake was associated with a significant increase in fecal lactobacilli abundance, suggesting a connection between exercise and a rise in lactobacilli abundance. Moreover, physical activity has improved weight-related parameters and led to increased plasma and mRNA adiponectin levels. Ghrelin and leptin plasma levels were unaltered. Taken together, our results demonstrate that effect of physical activity on adiposity even during unhealthy feeding patterns is accompanied by increased lactobacilli abundance in the fecal microbiota population. |
| first_indexed | 2024-04-11T10:42:54Z |
| format | Article |
| id | doaj.art-0ba9d7d3ec1b4d199e8ae6cae9a0bc64 |
| institution | Directory Open Access Journal |
| issn | 2391-5412 |
| language | English |
| last_indexed | 2024-04-11T10:42:54Z |
| publishDate | 2022-06-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Life Sciences |
| spelling | doaj.art-0ba9d7d3ec1b4d199e8ae6cae9a0bc642022-12-22T04:29:08ZengDe GruyterOpen Life Sciences2391-54122022-06-0117168669410.1515/biol-2022-0070Physical activity enhances fecal lactobacilli in rats chronically drinking sweetened cola beverageMarusakova Margareta0Dudik Boris1Hadova Katarina2Kmecova Zuzana3Kralova Eva4Krenek Peter5Bilkova Andrea6Klimas Jan7Department of Pharmacology and Toxicology, Comenius University Bratislava, Bratislava, SlovakiaDepartment of Cell and Molecular Biology of Drugs, Comenius University Bratislava, Bratislava, SlovakiaDepartment of Pharmacology and Toxicology, Comenius University Bratislava, Bratislava, SlovakiaDepartment of Pharmacology and Toxicology, Comenius University Bratislava, Bratislava, SlovakiaDepartment of Pharmacology and Toxicology, Comenius University Bratislava, Bratislava, SlovakiaDepartment of Pharmacology and Toxicology, Comenius University Bratislava, Bratislava, SlovakiaDepartment of Cell and Molecular Biology of Drugs, Comenius University Bratislava, Bratislava, SlovakiaDepartment of Pharmacology and Toxicology, Comenius University Bratislava, Bratislava, SlovakiaOverweight and obesity have been linked with increased intake of sugar-sweetened beverages. On the other hand, physical activity has been known to lead to weight loss. Therefore, we hypothesized that exercise might influence the Lactobacillus population in fecal microbiota as their changed abundance is often associated with shifts in the physical activity and diet. In our experiment, Wistar rats were allocated into groups with normal feed or added sugar-sweetened beverages with or without access to a running wheel. Interestingly, only a combination of physical activity and sweetened beverage intake was associated with a significant increase in fecal lactobacilli abundance, suggesting a connection between exercise and a rise in lactobacilli abundance. Moreover, physical activity has improved weight-related parameters and led to increased plasma and mRNA adiponectin levels. Ghrelin and leptin plasma levels were unaltered. Taken together, our results demonstrate that effect of physical activity on adiposity even during unhealthy feeding patterns is accompanied by increased lactobacilli abundance in the fecal microbiota population.https://doi.org/10.1515/biol-2022-0070overweightsweetened beveragephysical activityfecal lactobacillus abundanceadiponectin |
| spellingShingle | Marusakova Margareta Dudik Boris Hadova Katarina Kmecova Zuzana Kralova Eva Krenek Peter Bilkova Andrea Klimas Jan Physical activity enhances fecal lactobacilli in rats chronically drinking sweetened cola beverage Open Life Sciences overweight sweetened beverage physical activity fecal lactobacillus abundance adiponectin |
| title | Physical activity enhances fecal lactobacilli in rats chronically drinking sweetened cola beverage |
| title_full | Physical activity enhances fecal lactobacilli in rats chronically drinking sweetened cola beverage |
| title_fullStr | Physical activity enhances fecal lactobacilli in rats chronically drinking sweetened cola beverage |
| title_full_unstemmed | Physical activity enhances fecal lactobacilli in rats chronically drinking sweetened cola beverage |
| title_short | Physical activity enhances fecal lactobacilli in rats chronically drinking sweetened cola beverage |
| title_sort | physical activity enhances fecal lactobacilli in rats chronically drinking sweetened cola beverage |
| topic | overweight sweetened beverage physical activity fecal lactobacillus abundance adiponectin |
| url | https://doi.org/10.1515/biol-2022-0070 |
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