Polypoidal Choroidal Vasculopathy Associated with Optic Disc Coloboma
Purpose: To report a case of polypoidal choroidal vasculopathy associated with optic disc coloboma. Methods: Case report. Results: A 50-year-old woman presented with optic disc coloboma and retinochoroidal coloboma associated with subretinal hemorrhage and serous retinal detachment (SRD) in her left...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2018-01-01
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| Series: | Case Reports in Ophthalmology |
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| Online Access: | https://www.karger.com/Article/FullText/485966 |
| _version_ | 1818948748895584256 |
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| author | Yumiko Nakano Akiko Miki Shigeru Honda Makoto Nakamura |
| author_facet | Yumiko Nakano Akiko Miki Shigeru Honda Makoto Nakamura |
| author_sort | Yumiko Nakano |
| collection | DOAJ |
| description | Purpose: To report a case of polypoidal choroidal vasculopathy associated with optic disc coloboma. Methods: Case report. Results: A 50-year-old woman presented with optic disc coloboma and retinochoroidal coloboma associated with subretinal hemorrhage and serous retinal detachment (SRD) in her left eye. Optical coherence tomography (OCT) confirmed SRD at the macula and showed a sharply elevated retinal epithelial detachment at the choroidal excavation. OCT also revealed choroidal cavitation along the temporal side of the optic coloboma. Fluorescein angiography showed hyperfluorescent dye leakage and indocyanine green angiography revealed polypoidal lesions. We diagnosed polypoidal choroidal vasculopathy (PCV). PCV was located at the end of the choroidal cavitation. Her left eye was treated with an intraocular injection of the anti-vascular endothelial growth factor aflibercept (2 mg). Photodynamic therapy was performed using the standard protocol 1 week after the intravitreal application of aflibercept. One month after the combined treatment, OCT showed completely resolved SRD and her symptoms disappeared. Her best-corrected visual acuity remained stable and no recurrence was found during a 12-month follow-up period. Conclusion: PCV associated with optic disc coloboma has not been previously reported. The morphological abnormality of choroidal cavitation and choroidal excavation connecting with optic disc coloboma may contribute to the development of PCV in this case. |
| first_indexed | 2024-12-20T08:51:44Z |
| format | Article |
| id | doaj.art-0baad6de557840c8bb5cd401fa671925 |
| institution | Directory Open Access Journal |
| issn | 1663-2699 |
| language | English |
| last_indexed | 2024-12-20T08:51:44Z |
| publishDate | 2018-01-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Ophthalmology |
| spelling | doaj.art-0baad6de557840c8bb5cd401fa6719252022-12-21T19:46:06ZengKarger PublishersCase Reports in Ophthalmology1663-26992018-01-01919810110.1159/000485966485966Polypoidal Choroidal Vasculopathy Associated with Optic Disc ColobomaYumiko NakanoAkiko MikiShigeru HondaMakoto NakamuraPurpose: To report a case of polypoidal choroidal vasculopathy associated with optic disc coloboma. Methods: Case report. Results: A 50-year-old woman presented with optic disc coloboma and retinochoroidal coloboma associated with subretinal hemorrhage and serous retinal detachment (SRD) in her left eye. Optical coherence tomography (OCT) confirmed SRD at the macula and showed a sharply elevated retinal epithelial detachment at the choroidal excavation. OCT also revealed choroidal cavitation along the temporal side of the optic coloboma. Fluorescein angiography showed hyperfluorescent dye leakage and indocyanine green angiography revealed polypoidal lesions. We diagnosed polypoidal choroidal vasculopathy (PCV). PCV was located at the end of the choroidal cavitation. Her left eye was treated with an intraocular injection of the anti-vascular endothelial growth factor aflibercept (2 mg). Photodynamic therapy was performed using the standard protocol 1 week after the intravitreal application of aflibercept. One month after the combined treatment, OCT showed completely resolved SRD and her symptoms disappeared. Her best-corrected visual acuity remained stable and no recurrence was found during a 12-month follow-up period. Conclusion: PCV associated with optic disc coloboma has not been previously reported. The morphological abnormality of choroidal cavitation and choroidal excavation connecting with optic disc coloboma may contribute to the development of PCV in this case.https://www.karger.com/Article/FullText/485966CavitationColobomaPolypoidal choroidal vasculopathyPhotodynamic therapy |
| spellingShingle | Yumiko Nakano Akiko Miki Shigeru Honda Makoto Nakamura Polypoidal Choroidal Vasculopathy Associated with Optic Disc Coloboma Case Reports in Ophthalmology Cavitation Coloboma Polypoidal choroidal vasculopathy Photodynamic therapy |
| title | Polypoidal Choroidal Vasculopathy Associated with Optic Disc Coloboma |
| title_full | Polypoidal Choroidal Vasculopathy Associated with Optic Disc Coloboma |
| title_fullStr | Polypoidal Choroidal Vasculopathy Associated with Optic Disc Coloboma |
| title_full_unstemmed | Polypoidal Choroidal Vasculopathy Associated with Optic Disc Coloboma |
| title_short | Polypoidal Choroidal Vasculopathy Associated with Optic Disc Coloboma |
| title_sort | polypoidal choroidal vasculopathy associated with optic disc coloboma |
| topic | Cavitation Coloboma Polypoidal choroidal vasculopathy Photodynamic therapy |
| url | https://www.karger.com/Article/FullText/485966 |
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