Contribution of Imaging to Organs at Risk Dose during Lung Stereotactic Body Radiation Therapy
Background: The use of imaging is indispensable in modern radiation therapy, both for simulation and treatment delivery. For safe and sure utilization, dose delivery from imaging must be evaluated. Objective: This study aims to investigate the dose to organ at risk (OAR) delivered by imaging during...
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2021-04-01
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| Series: | Journal of Biomedical Physics and Engineering |
| Subjects: | |
| Online Access: | https://jbpe.sums.ac.ir/article_47302_a25340b481fed7710a5379905083ef90.pdf |
| _version_ | 1831586252869074944 |
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| author | Milovan Savanovic François Gardavaud Dražan Jaroš Bénédicte Lonkuta Matthias Barral François Henri Cornelis Jean-Noël Foulquier |
| author_facet | Milovan Savanovic François Gardavaud Dražan Jaroš Bénédicte Lonkuta Matthias Barral François Henri Cornelis Jean-Noël Foulquier |
| author_sort | Milovan Savanovic |
| collection | DOAJ |
| description | Background: The use of imaging is indispensable in modern radiation therapy, both for simulation and treatment delivery. For safe and sure utilization, dose delivery from imaging must be evaluated. Objective: This study aims to investigate the dose to organ at risk (OAR) delivered by imaging during lung stereotactic body radiation therapy (SBRT) and to evaluate its contribution to the treatment total dose.Material and Methods: In this retrospectively study, imaging total dose to organs at risk (OARs) (spinal cord, esophagus, lungs, and heart) and effective dose were retrospectively evaluated from 100 consecutive patients of a single institution who had lung SBRT. For each patient, dose was estimated using Monte-Carlo convolution for helical computed tomography (helical CT), Four-Dimensional CT (4D-CT), and kilovoltage Cone-Beam CT (kV-CBCT). Helical CT and kV-CBCT dose were evaluated for the entire thorax acquisition, while 4D-CT dose was analyzed on upper lobe (UL) or lower lobe (LL) acquisition. Treatment dose was extracted from treatment planning system and compared to imaging total dose. Results: Imaging total dose maximum values were 117 mGy to the spinal cord, 127 mGy to the esophagus, 176 mGy to the lungs and 193 mGy to the heart. The maximum effective dose was 19.65 mSv for helical CT, 10.62 mSv for kV-CBCT, 25.95 mSv and 38.45 mSv for 4D-CT in UL and LL regions, respectively. Depending on OAR, treatment total dose was higher from 1.7 to 8.2 times than imaging total dose. Imaging total dose contributed only to 0.3% of treatment total dose. Conclusion: Imaging dose delivered with 4D-CT to the OARs is higher than those of others modalities. The heart received the highest imaging dose for both UL and LL. Total imaging dose is negligible since it contributed only to 0.3% of treatment total dose. |
| first_indexed | 2024-12-17T21:33:08Z |
| format | Article |
| id | doaj.art-0badfdca2a964eb8977a60e1467b2159 |
| institution | Directory Open Access Journal |
| issn | 2251-7200 2251-7200 |
| language | English |
| last_indexed | 2024-12-17T21:33:08Z |
| publishDate | 2021-04-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Journal of Biomedical Physics and Engineering |
| spelling | doaj.art-0badfdca2a964eb8977a60e1467b21592022-12-21T21:31:49ZengShiraz University of Medical SciencesJournal of Biomedical Physics and Engineering2251-72002251-72002021-04-0111212513410.31661/jbpe.v0i0.2009-117347302Contribution of Imaging to Organs at Risk Dose during Lung Stereotactic Body Radiation TherapyMilovan Savanovic0François Gardavaud1Dražan Jaroš2Bénédicte Lonkuta3Matthias Barral4François Henri Cornelis5Jean-Noël Foulquier6PhD Candidate, Department of Radiation Oncology, Tenon Hospital, 75020 Paris, FrancePhD Candidate, Department of Radiology, Tenon Hospital, 75020 Paris, FrancePhD Candidate, Affidea, International Medical Centers, Center for Radiotherapy, 78000 Banja Luka, Bosnia and HerzegovinaMSc, Department of Radiology, Tenon Hospital, 75020 Paris, FranceMD, Department of Radiology, Tenon Hospital, 75020 Paris, FrancePhD, Department of Radiology, Tenon Hospital, 75020 Paris, FrancePhD, Department of Radiation Oncology, Tenon Hospital, 75020 Paris, FranceBackground: The use of imaging is indispensable in modern radiation therapy, both for simulation and treatment delivery. For safe and sure utilization, dose delivery from imaging must be evaluated. Objective: This study aims to investigate the dose to organ at risk (OAR) delivered by imaging during lung stereotactic body radiation therapy (SBRT) and to evaluate its contribution to the treatment total dose.Material and Methods: In this retrospectively study, imaging total dose to organs at risk (OARs) (spinal cord, esophagus, lungs, and heart) and effective dose were retrospectively evaluated from 100 consecutive patients of a single institution who had lung SBRT. For each patient, dose was estimated using Monte-Carlo convolution for helical computed tomography (helical CT), Four-Dimensional CT (4D-CT), and kilovoltage Cone-Beam CT (kV-CBCT). Helical CT and kV-CBCT dose were evaluated for the entire thorax acquisition, while 4D-CT dose was analyzed on upper lobe (UL) or lower lobe (LL) acquisition. Treatment dose was extracted from treatment planning system and compared to imaging total dose. Results: Imaging total dose maximum values were 117 mGy to the spinal cord, 127 mGy to the esophagus, 176 mGy to the lungs and 193 mGy to the heart. The maximum effective dose was 19.65 mSv for helical CT, 10.62 mSv for kV-CBCT, 25.95 mSv and 38.45 mSv for 4D-CT in UL and LL regions, respectively. Depending on OAR, treatment total dose was higher from 1.7 to 8.2 times than imaging total dose. Imaging total dose contributed only to 0.3% of treatment total dose. Conclusion: Imaging dose delivered with 4D-CT to the OARs is higher than those of others modalities. The heart received the highest imaging dose for both UL and LL. Total imaging dose is negligible since it contributed only to 0.3% of treatment total dose.https://jbpe.sums.ac.ir/article_47302_a25340b481fed7710a5379905083ef90.pdflungorgans at risk exposurecomputed tomographyfour-dimensional computed tomographycone-beam computed tomographystereotactic body radiation therapy |
| spellingShingle | Milovan Savanovic François Gardavaud Dražan Jaroš Bénédicte Lonkuta Matthias Barral François Henri Cornelis Jean-Noël Foulquier Contribution of Imaging to Organs at Risk Dose during Lung Stereotactic Body Radiation Therapy Journal of Biomedical Physics and Engineering lung organs at risk exposure computed tomography four-dimensional computed tomography cone-beam computed tomography stereotactic body radiation therapy |
| title | Contribution of Imaging to Organs at Risk Dose during Lung Stereotactic Body Radiation Therapy |
| title_full | Contribution of Imaging to Organs at Risk Dose during Lung Stereotactic Body Radiation Therapy |
| title_fullStr | Contribution of Imaging to Organs at Risk Dose during Lung Stereotactic Body Radiation Therapy |
| title_full_unstemmed | Contribution of Imaging to Organs at Risk Dose during Lung Stereotactic Body Radiation Therapy |
| title_short | Contribution of Imaging to Organs at Risk Dose during Lung Stereotactic Body Radiation Therapy |
| title_sort | contribution of imaging to organs at risk dose during lung stereotactic body radiation therapy |
| topic | lung organs at risk exposure computed tomography four-dimensional computed tomography cone-beam computed tomography stereotactic body radiation therapy |
| url | https://jbpe.sums.ac.ir/article_47302_a25340b481fed7710a5379905083ef90.pdf |
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