Viruses, dendritic cells and the lung
<p>Abstract</p> <p>The interaction between viruses and dendritic cells (DCs) is varied and complex. DCs are key elements in the development of a host response to pathogens such as viruses, but viruses have developed survival tactics to either evade or diminish the immune system tha...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2001-06-01
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| Series: | Respiratory Research |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1186/rr63 |
| _version_ | 1818565035749801984 |
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| author | Graham Barney S Peebles R Stokes |
| author_facet | Graham Barney S Peebles R Stokes |
| author_sort | Graham Barney S |
| collection | DOAJ |
| description | <p>Abstract</p> <p>The interaction between viruses and dendritic cells (DCs) is varied and complex. DCs are key elements in the development of a host response to pathogens such as viruses, but viruses have developed survival tactics to either evade or diminish the immune system that functions to kill and eliminate these micro-organisms. In the present review we summarize current concepts regarding the function of DCs in the immune system, our understanding of how viruses alter DC function to attenuate both the virus-specific and global immune response, and how we may be able to exploit DC function to prevent or treat viral infections.</p> |
| first_indexed | 2024-12-14T01:36:12Z |
| format | Article |
| id | doaj.art-0bb467c4bcc142e787c80dbb7bd65be6 |
| institution | Directory Open Access Journal |
| issn | 1465-9921 |
| language | English |
| last_indexed | 2024-12-14T01:36:12Z |
| publishDate | 2001-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Respiratory Research |
| spelling | doaj.art-0bb467c4bcc142e787c80dbb7bd65be62022-12-21T23:21:52ZengBMCRespiratory Research1465-99212001-06-012424524910.1186/rr63Viruses, dendritic cells and the lungGraham Barney SPeebles R Stokes<p>Abstract</p> <p>The interaction between viruses and dendritic cells (DCs) is varied and complex. DCs are key elements in the development of a host response to pathogens such as viruses, but viruses have developed survival tactics to either evade or diminish the immune system that functions to kill and eliminate these micro-organisms. In the present review we summarize current concepts regarding the function of DCs in the immune system, our understanding of how viruses alter DC function to attenuate both the virus-specific and global immune response, and how we may be able to exploit DC function to prevent or treat viral infections.</p>http://dx.doi.org/10.1186/rr63dendritic cellinflammationlungvirus |
| spellingShingle | Graham Barney S Peebles R Stokes Viruses, dendritic cells and the lung Respiratory Research dendritic cell inflammation lung virus |
| title | Viruses, dendritic cells and the lung |
| title_full | Viruses, dendritic cells and the lung |
| title_fullStr | Viruses, dendritic cells and the lung |
| title_full_unstemmed | Viruses, dendritic cells and the lung |
| title_short | Viruses, dendritic cells and the lung |
| title_sort | viruses dendritic cells and the lung |
| topic | dendritic cell inflammation lung virus |
| url | http://dx.doi.org/10.1186/rr63 |
| work_keys_str_mv | AT grahambarneys virusesdendriticcellsandthelung AT peeblesrstokes virusesdendriticcellsandthelung |