Mapping Research on miRNAs in Cancer: A Global Data Analysis and Bibliometric Profiling Analysis
miRNAs biomarkers are emerging as an essential part of clinical oncology. Their oncogenic and tumour suppressor properties playing a role in malignancy has generated interest in their potential for use in disease prognosis. While several studies on miRNA have been carried out across the globe, evalu...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Pathophysiology |
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| Online Access: | https://www.mdpi.com/1873-149X/29/1/7 |
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| author | Peter Shaw Kartik Lokhotiya Chellan Kumarasamy Krishnan Sunil Deepa Suresh Sameep Shetty Gothandam Kodiveri Muthukaliannan Siddhartha Baxi Ravishankar Ram Mani Palanisamy Sivanandy Harish C. Chandramoorthy Madan Mohan Gupta Suja Samiappan Rama Jayaraj |
| author_facet | Peter Shaw Kartik Lokhotiya Chellan Kumarasamy Krishnan Sunil Deepa Suresh Sameep Shetty Gothandam Kodiveri Muthukaliannan Siddhartha Baxi Ravishankar Ram Mani Palanisamy Sivanandy Harish C. Chandramoorthy Madan Mohan Gupta Suja Samiappan Rama Jayaraj |
| author_sort | Peter Shaw |
| collection | DOAJ |
| description | miRNAs biomarkers are emerging as an essential part of clinical oncology. Their oncogenic and tumour suppressor properties playing a role in malignancy has generated interest in their potential for use in disease prognosis. While several studies on miRNA have been carried out across the globe, evaluating the clinical implications of miRNAs in cancer diagnosis and prognosis research has currently not been attempted. A study delineating the area of miRNA research, including the topics presently being focused on, the seminal papers in this field, and the direction of research interest, does not exist. This study aims to conduct a large-scale, global data analysis and bibliometric profiling analysis of studies to evaluate the research output of clinical implications of miRNAs in cancer diagnosis and prognosis listed in the SCOPUS database. A systematic search strategy was followed to identify and extract all relevant studies, subsequently analysed to generate a bibliometric map. SPSS software (version 27) was used to calculate bibliometric indicators or parameters for analysis, such as year and country of affiliation with leading authors, journals, and institutions. It is also used to analyse annual research outputs, including total citations and the number of times it has been cited with productive nations and H-index. The number of global research articles retrieved for miRNA-Cancer research over the study period 2003 to 2019 was 18,636. Between 2012 and 2019, the growth rate of global publications is six times (<i>n</i> = 15,959; 90.71 percent articles) that of 2003 to 2011. (2704; 9.29 per cent articles). China published the most publications in the field of miRNA in cancer (<i>n</i> = 7782; 41%), while the United States had the most citations (<i>n</i> = 327,538; 48%) during the time span. Of these journals, Oncotarget has the highest percentage of article publications. The journal Cancer Research had the most citations (<i>n</i> = 41,876), with 6.20 per cent (<i>n</i> = 41,876). This study revealed a wide variety of journals in which miRNA-Cancer research are published; these bibliometric parameters exhibit crucial clinical information on performance assessment of research productivity and quality of research output. Therefore, this study provides a helpful reference for clinical oncologists, cancer scientists, policy decision-makers and clinical data researchers. |
| first_indexed | 2024-03-09T13:01:25Z |
| format | Article |
| id | doaj.art-0bb5a98d10464638bec617a378cecc44 |
| institution | Directory Open Access Journal |
| issn | 1873-149X |
| language | English |
| last_indexed | 2024-03-09T13:01:25Z |
| publishDate | 2022-02-01 |
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| series | Pathophysiology |
| spelling | doaj.art-0bb5a98d10464638bec617a378cecc442023-11-30T21:53:18ZengMDPI AGPathophysiology1873-149X2022-02-01291668010.3390/pathophysiology29010007Mapping Research on miRNAs in Cancer: A Global Data Analysis and Bibliometric Profiling AnalysisPeter Shaw0Kartik Lokhotiya1Chellan Kumarasamy2Krishnan Sunil3Deepa Suresh4Sameep Shetty5Gothandam Kodiveri Muthukaliannan6Siddhartha Baxi7Ravishankar Ram Mani8Palanisamy Sivanandy9Harish C. Chandramoorthy10Madan Mohan Gupta11Suja Samiappan12Rama Jayaraj13Oujiang Laboratory, Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325000, ChinaSchool of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore 632014, IndiaSchool of Health and Medical Sciences, Curtin University, Perth 6102, AustraliaDepartment of Radiation Oncology, Mayo Clinic Florida, Jacksonville, FL 32224, USADivision of Endocrinology, Department of Internal Medicine, Mayo Clinic Florida, Jacksonville, FL 32224, USADepartment of Oral and Maxillofacial Surgery, Manipal College of Dental Sciences, Mangalore, Manipal Academy of Higher Education, A Constituent of MAHE, Manipal 576104, IndiaSchool of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore 632014, IndiaGenesis Care Gold Coast Radiation Oncologist, John Flynn Hospital, Tugun 4224, AustraliaDepartment of Pharmaceutical Biology, Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur 56000, MalaysiaDepartment of Pharmacy Practice, School of Pharmacy, International Medical University, Kuala Lumpur 57000, MalaysiaStem Cells and Regenerative Medicine Unit, Department of Microbiology and Clinical Parasitology, College of Medicine, King Khalid University, Abha 56000, Saudi ArabiaSchool of Pharmacy, Faculty of Medical Sciences, The University of the West Indies, St. Augustine 3303, Trinidad and TobagoDepartment of Biochemistry, Bharathiar University, Coimbatore 641046, IndiaNorthern Territory Institute of Research and Training, Tiwi 0810, AustraliamiRNAs biomarkers are emerging as an essential part of clinical oncology. Their oncogenic and tumour suppressor properties playing a role in malignancy has generated interest in their potential for use in disease prognosis. While several studies on miRNA have been carried out across the globe, evaluating the clinical implications of miRNAs in cancer diagnosis and prognosis research has currently not been attempted. A study delineating the area of miRNA research, including the topics presently being focused on, the seminal papers in this field, and the direction of research interest, does not exist. This study aims to conduct a large-scale, global data analysis and bibliometric profiling analysis of studies to evaluate the research output of clinical implications of miRNAs in cancer diagnosis and prognosis listed in the SCOPUS database. A systematic search strategy was followed to identify and extract all relevant studies, subsequently analysed to generate a bibliometric map. SPSS software (version 27) was used to calculate bibliometric indicators or parameters for analysis, such as year and country of affiliation with leading authors, journals, and institutions. It is also used to analyse annual research outputs, including total citations and the number of times it has been cited with productive nations and H-index. The number of global research articles retrieved for miRNA-Cancer research over the study period 2003 to 2019 was 18,636. Between 2012 and 2019, the growth rate of global publications is six times (<i>n</i> = 15,959; 90.71 percent articles) that of 2003 to 2011. (2704; 9.29 per cent articles). China published the most publications in the field of miRNA in cancer (<i>n</i> = 7782; 41%), while the United States had the most citations (<i>n</i> = 327,538; 48%) during the time span. Of these journals, Oncotarget has the highest percentage of article publications. The journal Cancer Research had the most citations (<i>n</i> = 41,876), with 6.20 per cent (<i>n</i> = 41,876). This study revealed a wide variety of journals in which miRNA-Cancer research are published; these bibliometric parameters exhibit crucial clinical information on performance assessment of research productivity and quality of research output. Therefore, this study provides a helpful reference for clinical oncologists, cancer scientists, policy decision-makers and clinical data researchers.https://www.mdpi.com/1873-149X/29/1/7bibliometric analysiscancermiRNAclinical diagnosticsclinical prognostics |
| spellingShingle | Peter Shaw Kartik Lokhotiya Chellan Kumarasamy Krishnan Sunil Deepa Suresh Sameep Shetty Gothandam Kodiveri Muthukaliannan Siddhartha Baxi Ravishankar Ram Mani Palanisamy Sivanandy Harish C. Chandramoorthy Madan Mohan Gupta Suja Samiappan Rama Jayaraj Mapping Research on miRNAs in Cancer: A Global Data Analysis and Bibliometric Profiling Analysis Pathophysiology bibliometric analysis cancer miRNA clinical diagnostics clinical prognostics |
| title | Mapping Research on miRNAs in Cancer: A Global Data Analysis and Bibliometric Profiling Analysis |
| title_full | Mapping Research on miRNAs in Cancer: A Global Data Analysis and Bibliometric Profiling Analysis |
| title_fullStr | Mapping Research on miRNAs in Cancer: A Global Data Analysis and Bibliometric Profiling Analysis |
| title_full_unstemmed | Mapping Research on miRNAs in Cancer: A Global Data Analysis and Bibliometric Profiling Analysis |
| title_short | Mapping Research on miRNAs in Cancer: A Global Data Analysis and Bibliometric Profiling Analysis |
| title_sort | mapping research on mirnas in cancer a global data analysis and bibliometric profiling analysis |
| topic | bibliometric analysis cancer miRNA clinical diagnostics clinical prognostics |
| url | https://www.mdpi.com/1873-149X/29/1/7 |
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