DNA repair as a shared hallmark in cancer and ageing
Increasing evidence demonstrates that DNA damage and genome instability play a crucial role in ageing. Mammalian cells have developed a wide range of complex and well‐orchestrated DNA repair pathways to respond to and resolve many different types of DNA lesions that occur from exogenous and endogeno...
Main Authors: | Thomas L. Clarke, Raul Mostoslavsky |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2022-09-01
|
Series: | Molecular Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1002/1878-0261.13285 |
Similar Items
-
DNA damage—how and why we age?
by: Matt Yousefzadeh, et al.
Published: (2021-01-01) -
A score of DNA damage repair pathway with the predictive ability for chemotherapy and immunotherapy is strongly associated with immune signaling pathway in pan-cancer
by: Ke Ding, et al.
Published: (2022-08-01) -
Aldehyde-induced DNA-protein crosslinks- DNA damage, repair and mutagenesis
by: Thomas Blouin, et al.
Published: (2024-09-01) -
DNA damage response and cancer therapeutics through the lens of the Fanconi Anemia DNA repair pathway
by: Sonali Bhattacharjee, et al.
Published: (2017-10-01) -
Chromosomal Instability as Enabling Feature and Central Hallmark of Breast Cancer
by: Castellanos G, et al.
Published: (2023-03-01)