Ejection Fraction Estimation from Echocardiograms Using Optimal Left Ventricle Feature Extraction Based on Clinical Methods

Echocardiography is one of the imaging systems most often utilized for assessing heart anatomy and function. Left ventricle ejection fraction (LVEF) is an important clinical variable assessed from echocardiography via the measurement of left ventricle (LV) parameters. Significant inter-observer and...

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Main Authors: Samana Batool, Imtiaz Ahmad Taj, Mubeen Ghafoor
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/13/13/2155
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author Samana Batool
Imtiaz Ahmad Taj
Mubeen Ghafoor
author_facet Samana Batool
Imtiaz Ahmad Taj
Mubeen Ghafoor
author_sort Samana Batool
collection DOAJ
description Echocardiography is one of the imaging systems most often utilized for assessing heart anatomy and function. Left ventricle ejection fraction (LVEF) is an important clinical variable assessed from echocardiography via the measurement of left ventricle (LV) parameters. Significant inter-observer and intra-observer variability is seen when LVEF is quantified by cardiologists using huge echocardiography data. Machine learning algorithms have the capability to analyze such extensive datasets and identify intricate patterns of structure and function of the heart that highly skilled observers might overlook, hence paving the way for computer-assisted diagnostics in this field. In this study, LV segmentation is performed on echocardiogram data followed by feature extraction from the left ventricle based on clinical methods. The extracted features are then subjected to analysis using both neural networks and traditional machine learning algorithms to estimate the LVEF. The results indicate that employing machine learning techniques on the extracted features from the left ventricle leads to higher accuracy than the utilization of Simpson’s method for estimating the LVEF. The evaluations are performed on a publicly available echocardiogram dataset, EchoNet-Dynamic. The best results are obtained when DeepLab, a convolutional neural network architecture, is used for LV segmentation along with Long Short-Term Memory Networks (LSTM) for the regression of LVEF, obtaining a dice similarity coefficient of 0.92 and a mean absolute error of 5.736%.
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spelling doaj.art-0bb81aeab66345c0b481a3d5049a8a312023-11-18T16:20:46ZengMDPI AGDiagnostics2075-44182023-06-011313215510.3390/diagnostics13132155Ejection Fraction Estimation from Echocardiograms Using Optimal Left Ventricle Feature Extraction Based on Clinical MethodsSamana Batool0Imtiaz Ahmad Taj1Mubeen Ghafoor2Electrical Engineering, Capital University of Science and Technology, Islamabad Expressway, Kahuta Road, Islamabad 44000, PakistanElectrical Engineering, Capital University of Science and Technology, Islamabad Expressway, Kahuta Road, Islamabad 44000, PakistanSchool of Computer Science, University of Lincoln, Brayford Way, Brayford, Pool, Lincoln LN6 7TS, UKEchocardiography is one of the imaging systems most often utilized for assessing heart anatomy and function. Left ventricle ejection fraction (LVEF) is an important clinical variable assessed from echocardiography via the measurement of left ventricle (LV) parameters. Significant inter-observer and intra-observer variability is seen when LVEF is quantified by cardiologists using huge echocardiography data. Machine learning algorithms have the capability to analyze such extensive datasets and identify intricate patterns of structure and function of the heart that highly skilled observers might overlook, hence paving the way for computer-assisted diagnostics in this field. In this study, LV segmentation is performed on echocardiogram data followed by feature extraction from the left ventricle based on clinical methods. The extracted features are then subjected to analysis using both neural networks and traditional machine learning algorithms to estimate the LVEF. The results indicate that employing machine learning techniques on the extracted features from the left ventricle leads to higher accuracy than the utilization of Simpson’s method for estimating the LVEF. The evaluations are performed on a publicly available echocardiogram dataset, EchoNet-Dynamic. The best results are obtained when DeepLab, a convolutional neural network architecture, is used for LV segmentation along with Long Short-Term Memory Networks (LSTM) for the regression of LVEF, obtaining a dice similarity coefficient of 0.92 and a mean absolute error of 5.736%.https://www.mdpi.com/2075-4418/13/13/2155medical imagingtransthoracic echocardiographyleft ventricle ejection fractionregressionmachine learningSimpson’s biplane method
spellingShingle Samana Batool
Imtiaz Ahmad Taj
Mubeen Ghafoor
Ejection Fraction Estimation from Echocardiograms Using Optimal Left Ventricle Feature Extraction Based on Clinical Methods
Diagnostics
medical imaging
transthoracic echocardiography
left ventricle ejection fraction
regression
machine learning
Simpson’s biplane method
title Ejection Fraction Estimation from Echocardiograms Using Optimal Left Ventricle Feature Extraction Based on Clinical Methods
title_full Ejection Fraction Estimation from Echocardiograms Using Optimal Left Ventricle Feature Extraction Based on Clinical Methods
title_fullStr Ejection Fraction Estimation from Echocardiograms Using Optimal Left Ventricle Feature Extraction Based on Clinical Methods
title_full_unstemmed Ejection Fraction Estimation from Echocardiograms Using Optimal Left Ventricle Feature Extraction Based on Clinical Methods
title_short Ejection Fraction Estimation from Echocardiograms Using Optimal Left Ventricle Feature Extraction Based on Clinical Methods
title_sort ejection fraction estimation from echocardiograms using optimal left ventricle feature extraction based on clinical methods
topic medical imaging
transthoracic echocardiography
left ventricle ejection fraction
regression
machine learning
Simpson’s biplane method
url https://www.mdpi.com/2075-4418/13/13/2155
work_keys_str_mv AT samanabatool ejectionfractionestimationfromechocardiogramsusingoptimalleftventriclefeatureextractionbasedonclinicalmethods
AT imtiazahmadtaj ejectionfractionestimationfromechocardiogramsusingoptimalleftventriclefeatureextractionbasedonclinicalmethods
AT mubeenghafoor ejectionfractionestimationfromechocardiogramsusingoptimalleftventriclefeatureextractionbasedonclinicalmethods