IMMUNE DISTURBANCES AND SUBSTANTIATION OF THEIR CORRECTION IN THE CHILDREN WITH CHRONIC GASTRODUODENITIS
Abstract. 72 patients and 30 healthy children of the age of 7-17 years were examined, aiming for substantiation of thymaline, vilon and ventramine application in treatment of chronic gastroduodenitis in children. Disbalance of cellular and humoral immunity and reduction of intensity of lymphocyte-pl...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
|
| Series: | Медицинская иммунология |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/81 |
| _version_ | 1797198137201262592 |
|---|---|
| author | V. A. Shcherbak Yu. A. Vitkovsky B. I. Kuznik |
| author_facet | V. A. Shcherbak Yu. A. Vitkovsky B. I. Kuznik |
| author_sort | V. A. Shcherbak |
| collection | DOAJ |
| description | Abstract. 72 patients and 30 healthy children of the age of 7-17 years were examined, aiming for substantiation of thymaline, vilon and ventramine application in treatment of chronic gastroduodenitis in children. Disbalance of cellular and humoral immunity and reduction of intensity of lymphocyte-platelet adhesions were established. An increase of IL-1β, IL-2, TNFα and IFNα concentration was registered in absence of IL-4 changes. Application of thymaline, vilon and ventramine essentially improves clinical course of disease, results in normalization of immune profile, reduced levels of proimflammatory cytokines, restoration of lymphocyte-platelet adhesions. |
| first_indexed | 2024-03-08T05:52:17Z |
| format | Article |
| id | doaj.art-0bc181d3cd9e44058f90295754b0057d |
| institution | Directory Open Access Journal |
| issn | 1563-0625 2313-741X |
| language | Russian |
| last_indexed | 2024-04-24T06:55:04Z |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj.art-0bc181d3cd9e44058f90295754b0057d2024-04-22T13:07:33ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-01101596610.15789/1563-0625-2008-1-59-6679IMMUNE DISTURBANCES AND SUBSTANTIATION OF THEIR CORRECTION IN THE CHILDREN WITH CHRONIC GASTRODUODENITISV. A. Shcherbak0Yu. A. Vitkovsky1B. I. Kuznik2ГОУ ВПО Читинская государственная медицинская академия, г. ЧитаГОУ ВПО Читинская государственная медицинская академия, г. ЧитаГОУ ВПО Читинская государственная медицинская академия, г. ЧитаAbstract. 72 patients and 30 healthy children of the age of 7-17 years were examined, aiming for substantiation of thymaline, vilon and ventramine application in treatment of chronic gastroduodenitis in children. Disbalance of cellular and humoral immunity and reduction of intensity of lymphocyte-platelet adhesions were established. An increase of IL-1β, IL-2, TNFα and IFNα concentration was registered in absence of IL-4 changes. Application of thymaline, vilon and ventramine essentially improves clinical course of disease, results in normalization of immune profile, reduced levels of proimflammatory cytokines, restoration of lymphocyte-platelet adhesions.https://www.mimmun.ru/mimmun/article/view/81childrengastroduodenitisimmunitycytokines |
| spellingShingle | V. A. Shcherbak Yu. A. Vitkovsky B. I. Kuznik IMMUNE DISTURBANCES AND SUBSTANTIATION OF THEIR CORRECTION IN THE CHILDREN WITH CHRONIC GASTRODUODENITIS Медицинская иммунология children gastroduodenitis immunity cytokines |
| title | IMMUNE DISTURBANCES AND SUBSTANTIATION OF THEIR CORRECTION IN THE CHILDREN WITH CHRONIC GASTRODUODENITIS |
| title_full | IMMUNE DISTURBANCES AND SUBSTANTIATION OF THEIR CORRECTION IN THE CHILDREN WITH CHRONIC GASTRODUODENITIS |
| title_fullStr | IMMUNE DISTURBANCES AND SUBSTANTIATION OF THEIR CORRECTION IN THE CHILDREN WITH CHRONIC GASTRODUODENITIS |
| title_full_unstemmed | IMMUNE DISTURBANCES AND SUBSTANTIATION OF THEIR CORRECTION IN THE CHILDREN WITH CHRONIC GASTRODUODENITIS |
| title_short | IMMUNE DISTURBANCES AND SUBSTANTIATION OF THEIR CORRECTION IN THE CHILDREN WITH CHRONIC GASTRODUODENITIS |
| title_sort | immune disturbances and substantiation of their correction in the children with chronic gastroduodenitis |
| topic | children gastroduodenitis immunity cytokines |
| url | https://www.mimmun.ru/mimmun/article/view/81 |
| work_keys_str_mv | AT vashcherbak immunedisturbancesandsubstantiationoftheircorrectioninthechildrenwithchronicgastroduodenitis AT yuavitkovsky immunedisturbancesandsubstantiationoftheircorrectioninthechildrenwithchronicgastroduodenitis AT bikuznik immunedisturbancesandsubstantiationoftheircorrectioninthechildrenwithchronicgastroduodenitis |