Research progress of neuromodulation in the treatment of Parkinson's disease
Parkinson's disease (PD) is a common degenerative neurological disorder, characterized by static tremor, bradykinesia, myotonia and postural abnormalities. Dopaminergic drugs are the main drugs in the treatment of PD, but long-term use will lead to drug efficacy loss, and even cause some advers...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science)
2024-02-01
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| Series: | Shanghai Jiaotong Daxue xuebao. Yixue ban |
| Subjects: | |
| Online Access: | https://xuebao.shsmu.edu.cn/CN/10.3969/j.issn.1674-8115.2024.02.012 |
| _version_ | 1797244957975642112 |
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| author | HU Canfang ZHONG Chuanyu CAO Li |
| author_facet | HU Canfang ZHONG Chuanyu CAO Li |
| author_sort | HU Canfang |
| collection | DOAJ |
| description | Parkinson's disease (PD) is a common degenerative neurological disorder, characterized by static tremor, bradykinesia, myotonia and postural abnormalities. Dopaminergic drugs are the main drugs in the treatment of PD, but long-term use will lead to drug efficacy loss, and even cause some adverse reactions such as dyskinesia and "on-off" phenomenon. Neuromodulation is a kind of biomedical engineering technology that can stimulate or inhibit the activity of brain neurons and regulate the changes of neuroplasticity by means of electric energy, magnetic field, ultrasound and other methods, so as to achieve treatment and improvement of diseases. In the non-drug treatment of PD, neuromodulation, as a new therapeutic means, has shown good efficacy, and has the advantages of small adverse reactions and easy tolerance. Based on this, this article reviews the research progress of several common neuromodulation in PD, including deep brain stimulation, transcranial magnetic stimulation, transcranial direct current stimulation and transcranial focused ultrasound. |
| first_indexed | 2024-04-24T19:19:16Z |
| format | Article |
| id | doaj.art-0bc50a8d62f049318fa045064a099ff4 |
| institution | Directory Open Access Journal |
| issn | 1674-8115 |
| language | zho |
| last_indexed | 2024-04-24T19:19:16Z |
| publishDate | 2024-02-01 |
| publisher | Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science) |
| record_format | Article |
| series | Shanghai Jiaotong Daxue xuebao. Yixue ban |
| spelling | doaj.art-0bc50a8d62f049318fa045064a099ff42024-03-26T03:15:46ZzhoEditorial Office of Journal of Shanghai Jiao Tong University (Medical Science)Shanghai Jiaotong Daxue xuebao. Yixue ban1674-81152024-02-0144225826310.3969/j.issn.1674-8115.2024.02.0121674-8115（2024）02-0258-06Research progress of neuromodulation in the treatment of Parkinson's diseaseHU Canfang0ZHONG Chuanyu1CAO Li2Department of Neurology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200233, ChinaDepartment of Ultrasound Medicine, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200233, ChinaDepartment of Neurology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200233, ChinaParkinson's disease (PD) is a common degenerative neurological disorder, characterized by static tremor, bradykinesia, myotonia and postural abnormalities. Dopaminergic drugs are the main drugs in the treatment of PD, but long-term use will lead to drug efficacy loss, and even cause some adverse reactions such as dyskinesia and "on-off" phenomenon. Neuromodulation is a kind of biomedical engineering technology that can stimulate or inhibit the activity of brain neurons and regulate the changes of neuroplasticity by means of electric energy, magnetic field, ultrasound and other methods, so as to achieve treatment and improvement of diseases. In the non-drug treatment of PD, neuromodulation, as a new therapeutic means, has shown good efficacy, and has the advantages of small adverse reactions and easy tolerance. Based on this, this article reviews the research progress of several common neuromodulation in PD, including deep brain stimulation, transcranial magnetic stimulation, transcranial direct current stimulation and transcranial focused ultrasound.https://xuebao.shsmu.edu.cn/CN/10.3969/j.issn.1674-8115.2024.02.012neuromodulationparkinson's disease (pd)deep brain stimulation (dbs)transcranial magnetic stimulation (tms)transcranial direct current stimulation (tdcs)transcranial focused ultrasound (tfus) |
| spellingShingle | HU Canfang ZHONG Chuanyu CAO Li Research progress of neuromodulation in the treatment of Parkinson's disease Shanghai Jiaotong Daxue xuebao. Yixue ban neuromodulation parkinson's disease (pd) deep brain stimulation (dbs) transcranial magnetic stimulation (tms) transcranial direct current stimulation (tdcs) transcranial focused ultrasound (tfus) |
| title | Research progress of neuromodulation in the treatment of Parkinson's disease |
| title_full | Research progress of neuromodulation in the treatment of Parkinson's disease |
| title_fullStr | Research progress of neuromodulation in the treatment of Parkinson's disease |
| title_full_unstemmed | Research progress of neuromodulation in the treatment of Parkinson's disease |
| title_short | Research progress of neuromodulation in the treatment of Parkinson's disease |
| title_sort | research progress of neuromodulation in the treatment of parkinson s disease |
| topic | neuromodulation parkinson's disease (pd) deep brain stimulation (dbs) transcranial magnetic stimulation (tms) transcranial direct current stimulation (tdcs) transcranial focused ultrasound (tfus) |
| url | https://xuebao.shsmu.edu.cn/CN/10.3969/j.issn.1674-8115.2024.02.012 |
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