Interleukin-35 Prevents the Elevation of the M1/M2 Ratio of Macrophages in Experimental Type 1 Diabetes

Interleukin-35 Prevents the Elevation of the M1/M2 Ratio of Macrophages in Experimental Type 1 Diabetes

Macrophages play an important role in the early development of type 1 diabetes (T1D). Based on the phenotype, macrophages can be classified into pro-inflammatory (M1) and anti-inflammatory (M2) macrophages. Despite intensive research in the field of macrophages and T1D, the kinetic response of M1/M2...

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Bibliographic Details
Main Authors: Zhengkang Luo, Charlotte Soläng, Rasmus Larsson, Kailash Singh
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
type 1 diabetes
macrophages (M1 and M2)
pDCs
IL-35
Online Access:https://www.mdpi.com/1422-0067/23/14/7970

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