Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat?
Ventilator-associated tracheobronchitis (VAT) is an infection commonly affecting mechanically ventilated intubated patients. Several studies suggest that VAT is associated with increased duration of mechanical ventilation (MV) and length of intensive care unit (ICU) stay, and a presumptive increase...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-01-01
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| Series: | Antibiotics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6382/9/2/51 |
| _version_ | 1828857679635808256 |
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| author | Despoina Koulenti Kostoula Arvaniti Mathew Judd Natasha Lalos Iona Tjoeng Elena Xu Apostolos Armaganidis Jeffrey Lipman |
| author_facet | Despoina Koulenti Kostoula Arvaniti Mathew Judd Natasha Lalos Iona Tjoeng Elena Xu Apostolos Armaganidis Jeffrey Lipman |
| author_sort | Despoina Koulenti |
| collection | DOAJ |
| description | Ventilator-associated tracheobronchitis (VAT) is an infection commonly affecting mechanically ventilated intubated patients. Several studies suggest that VAT is associated with increased duration of mechanical ventilation (MV) and length of intensive care unit (ICU) stay, and a presumptive increase in healthcare costs. Uncertainties remain, however, regarding the cost/benefit balance of VAT treatment. The aim of this narrative review is to discuss the two fundamental and inter-related dilemmas regarding VAT, i.e., (i) how to diagnose VAT? and (ii) should we treat VAT? If yes, should we treat all cases or only selected ones? How should we treat in terms of antibiotic choice, route, treatment duration? |
| first_indexed | 2024-12-13T01:42:40Z |
| format | Article |
| id | doaj.art-0bcd717bf24a4fb8b6a6396f3971d8d8 |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-12-13T01:42:40Z |
| publishDate | 2020-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-0bcd717bf24a4fb8b6a6396f3971d8d82022-12-22T00:03:43ZengMDPI AGAntibiotics2079-63822020-01-01925110.3390/antibiotics9020051antibiotics9020051Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat?Despoina Koulenti0Kostoula Arvaniti1Mathew Judd2Natasha Lalos3Iona Tjoeng4Elena Xu5Apostolos Armaganidis6Jeffrey Lipman7UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane 4029, AustraliaDepartment of Critical Care Medicine, ‘Papageorgiou’ General Hospital of Thessaloniki, Thessaloniki 56429, GreeceUQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane 4029, AustraliaUQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane 4029, AustraliaUQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane 4029, AustraliaUQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane 4029, Australia2nd Critical Care Department, ‘Attikon’ University Hospital, Athens 11632, GreeceUQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane 4029, AustraliaVentilator-associated tracheobronchitis (VAT) is an infection commonly affecting mechanically ventilated intubated patients. Several studies suggest that VAT is associated with increased duration of mechanical ventilation (MV) and length of intensive care unit (ICU) stay, and a presumptive increase in healthcare costs. Uncertainties remain, however, regarding the cost/benefit balance of VAT treatment. The aim of this narrative review is to discuss the two fundamental and inter-related dilemmas regarding VAT, i.e., (i) how to diagnose VAT? and (ii) should we treat VAT? If yes, should we treat all cases or only selected ones? How should we treat in terms of antibiotic choice, route, treatment duration?https://www.mdpi.com/2079-6382/9/2/51ventilator-associated tracheobronchitisvatdiagnosistreatmentinhaled antibiotics |
| spellingShingle | Despoina Koulenti Kostoula Arvaniti Mathew Judd Natasha Lalos Iona Tjoeng Elena Xu Apostolos Armaganidis Jeffrey Lipman Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat? Antibiotics ventilator-associated tracheobronchitis vat diagnosis treatment inhaled antibiotics |
| title | Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat? |
| title_full | Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat? |
| title_fullStr | Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat? |
| title_full_unstemmed | Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat? |
| title_short | Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat? |
| title_sort | ventilator associated tracheobronchitis to treat or not to treat |
| topic | ventilator-associated tracheobronchitis vat diagnosis treatment inhaled antibiotics |
| url | https://www.mdpi.com/2079-6382/9/2/51 |
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