Gene expression profiles define molecular subtypes of prostate cancer bone metastases with different outcomes and morphology traceable back to the primary tumor

Gene expression profiles define molecular subtypes of prostate cancer bone metastases with different outcomes and morphology traceable back to the primary tumor

Bone metastasis is the lethal end‐stage of prostate cancer (PC), but the biology of bone metastases is poorly understood. The overall aim of this study was therefore to explore molecular variability in PC bone metastases of potential importance for therapy. Specifically, genome‐wide expression profi...

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Bibliographic Details
Main Authors: Elin Thysell, Linda Vidman, Erik Bovinder Ylitalo, Emma Jernberg, Sead Crnalic, Diego Iglesias‐Gato, Amilcar Flores‐Morales, Pär Stattin, Lars Egevad, Anders Widmark, Patrik Rydén, Anders Bergh, Pernilla Wikström
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Molecular Oncology
Subjects:
bone metastasis
gene expression
gene set enrichment analysis
morphology
survival
unsupervised cluster analysis
Online Access:https://doi.org/10.1002/1878-0261.12526

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