Outcome of Facial Burn Injuries Treated by a Nanofibrous Temporary Epidermal Layer
Background: The face is commonly affected in thermal injuries, with a demand for proper recognition and the correct choice of treatment to guarantee optimal aesthetic and functional outcomes. It is highly vascularized and often heals conservatively, highlighting the particular relevance of conservat...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/16/5273 |
| _version_ | 1797584313136447488 |
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| author | Mauro Vasella Jan Cirebea Epameinondas Gousopoulos Anna Wang Riccardo Schweizer Matthias Waldner Gerrit Grieb Philipp Buehler Jan Alexander Plock Bong-Sung Kim |
| author_facet | Mauro Vasella Jan Cirebea Epameinondas Gousopoulos Anna Wang Riccardo Schweizer Matthias Waldner Gerrit Grieb Philipp Buehler Jan Alexander Plock Bong-Sung Kim |
| author_sort | Mauro Vasella |
| collection | DOAJ |
| description | Background: The face is commonly affected in thermal injuries, with a demand for proper recognition and the correct choice of treatment to guarantee optimal aesthetic and functional outcomes. It is highly vascularized and often heals conservatively, highlighting the particular relevance of conservative treatment modalities, many of which require daily re-applications or dressing changes, which can be painful and tedious for both the patient and the healthcare providers. Motivated by encouraging results of a novel temporary nanofibrous epidermal layer, we herein present a case series of this technology in a case series of patients suffering from facial burns and treated in our Burn Center. Patients and Methods: Patients with superficial partial-thickness facial burns and mixed pattern burns, which were treated with SpinCare<sup>™</sup>, an electrospun nanofibrous temporary epidermal layer, between 2019 and 2021, at our institution were analyzed retrospectively. The Manchester scar scale (MSS) and numeric rating scale (NRS) were used for scar, pain, and outcome evaluation at different time points by five independent board-certified plastic surgeons with profound experience in burn surgery. Results: Ten patients (m = 9; f = 1) were treated and evaluated retrospectively. The mean age was 38.8 ± years (SD ± 17.85). The mean healing time was 6.4 days (SD ± 1.56). The mean follow-up was 16.4 months (SD ± 11.33). The mean MSS score was 5.06 (SD ± 1.31), and the mean NRS Score for pain was significantly reduced from initially 7 to 0.875 upon application (mean (pre-application) 7 ± 0.7 and (application) 0.875 ± 1.26; <i>p</i> ≤ 0.0001). Patients reported a NRS score of 10 in terms of functional and cosmetic outcomes at their final follow-up appointment. No adverse effects were observed. Conclusions: The application of a nanofibrous temporary epidermal layer such as SpinCare<sup>™</sup> represents a relatively easy-to-use, well-tolerated, and effective alternative for the treatment of partial-thickness facial burns. |
| first_indexed | 2024-03-10T23:50:06Z |
| format | Article |
| id | doaj.art-0bd309beb2ed4be5a1251c635e7a7306 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T23:50:06Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-0bd309beb2ed4be5a1251c635e7a73062023-11-19T01:40:42ZengMDPI AGJournal of Clinical Medicine2077-03832023-08-011216527310.3390/jcm12165273Outcome of Facial Burn Injuries Treated by a Nanofibrous Temporary Epidermal LayerMauro Vasella0Jan Cirebea1Epameinondas Gousopoulos2Anna Wang3Riccardo Schweizer4Matthias Waldner5Gerrit Grieb6Philipp Buehler7Jan Alexander Plock8Bong-Sung Kim9Department of Plastic Surgery and Hand Surgery, University Hospital Zurich, 8091 Zurich, SwitzerlandDepartment of Plastic Surgery and Hand Surgery, University Hospital Zurich, 8091 Zurich, SwitzerlandDepartment of Plastic Surgery and Hand Surgery, University Hospital Zurich, 8091 Zurich, SwitzerlandDepartment of Plastic Surgery and Hand Surgery, University Hospital Zurich, 8091 Zurich, SwitzerlandDepartment of Plastic Surgery and Hand Surgery, University Hospital Zurich, 8091 Zurich, SwitzerlandDepartment of Plastic Surgery and Hand Surgery, University Hospital Zurich, 8091 Zurich, SwitzerlandDepartment of Plastic Surgery and Hand Surgery, Gemeinschaftskrankenhaus Havelhoehe, 14089 Berlin, GermanyCenter of Intensive Care Medicine, Cantonal Hospital Winterthur, 8400 Winterthur, SwitzerlandDepartment of Plastic Surgery and Hand Surgery, University Hospital Zurich, 8091 Zurich, SwitzerlandDepartment of Plastic Surgery and Hand Surgery, University Hospital Zurich, 8091 Zurich, SwitzerlandBackground: The face is commonly affected in thermal injuries, with a demand for proper recognition and the correct choice of treatment to guarantee optimal aesthetic and functional outcomes. It is highly vascularized and often heals conservatively, highlighting the particular relevance of conservative treatment modalities, many of which require daily re-applications or dressing changes, which can be painful and tedious for both the patient and the healthcare providers. Motivated by encouraging results of a novel temporary nanofibrous epidermal layer, we herein present a case series of this technology in a case series of patients suffering from facial burns and treated in our Burn Center. Patients and Methods: Patients with superficial partial-thickness facial burns and mixed pattern burns, which were treated with SpinCare<sup>™</sup>, an electrospun nanofibrous temporary epidermal layer, between 2019 and 2021, at our institution were analyzed retrospectively. The Manchester scar scale (MSS) and numeric rating scale (NRS) were used for scar, pain, and outcome evaluation at different time points by five independent board-certified plastic surgeons with profound experience in burn surgery. Results: Ten patients (m = 9; f = 1) were treated and evaluated retrospectively. The mean age was 38.8 ± years (SD ± 17.85). The mean healing time was 6.4 days (SD ± 1.56). The mean follow-up was 16.4 months (SD ± 11.33). The mean MSS score was 5.06 (SD ± 1.31), and the mean NRS Score for pain was significantly reduced from initially 7 to 0.875 upon application (mean (pre-application) 7 ± 0.7 and (application) 0.875 ± 1.26; <i>p</i> ≤ 0.0001). Patients reported a NRS score of 10 in terms of functional and cosmetic outcomes at their final follow-up appointment. No adverse effects were observed. Conclusions: The application of a nanofibrous temporary epidermal layer such as SpinCare<sup>™</sup> represents a relatively easy-to-use, well-tolerated, and effective alternative for the treatment of partial-thickness facial burns.https://www.mdpi.com/2077-0383/12/16/5273facial burnsconservative treatmentnanofibrous dressingtemporary dressing |
| spellingShingle | Mauro Vasella Jan Cirebea Epameinondas Gousopoulos Anna Wang Riccardo Schweizer Matthias Waldner Gerrit Grieb Philipp Buehler Jan Alexander Plock Bong-Sung Kim Outcome of Facial Burn Injuries Treated by a Nanofibrous Temporary Epidermal Layer Journal of Clinical Medicine facial burns conservative treatment nanofibrous dressing temporary dressing |
| title | Outcome of Facial Burn Injuries Treated by a Nanofibrous Temporary Epidermal Layer |
| title_full | Outcome of Facial Burn Injuries Treated by a Nanofibrous Temporary Epidermal Layer |
| title_fullStr | Outcome of Facial Burn Injuries Treated by a Nanofibrous Temporary Epidermal Layer |
| title_full_unstemmed | Outcome of Facial Burn Injuries Treated by a Nanofibrous Temporary Epidermal Layer |
| title_short | Outcome of Facial Burn Injuries Treated by a Nanofibrous Temporary Epidermal Layer |
| title_sort | outcome of facial burn injuries treated by a nanofibrous temporary epidermal layer |
| topic | facial burns conservative treatment nanofibrous dressing temporary dressing |
| url | https://www.mdpi.com/2077-0383/12/16/5273 |
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