Effectiveness of Second-look Flexible Ureteroscopy to Achieve A True Stone-Free Status in Retrograde Intrarenal Surgery

Objective:Residual stone fragments remain a challenging topic for urologists following retrograde intrarenal surgery (RIRS). This study aimed to investigate the effectiveness of second-look flexible ureteroscopy (URS) to achieve a true stone-free status and decrease stone-related events.Materials an...

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Main Authors: Oğuz Özden Cebeci, Tayyar Alp Özkan, Mustafa Savaş Yalçın, Özdal Dillioğlugil, İbrahim Çevik
Format: Article
Language:English
Published: Galenos Yayinevi 2022-03-01
Series:Journal of Urological Surgery
Subjects:
Online Access: http://jurolsurgery.org/archives/archive-detail/article-preview/effectiveness-of-second-look-flexible-ureteroscopy/51029
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author Oğuz Özden Cebeci
Tayyar Alp Özkan
Mustafa Savaş Yalçın
Özdal Dillioğlugil
İbrahim Çevik
author_facet Oğuz Özden Cebeci
Tayyar Alp Özkan
Mustafa Savaş Yalçın
Özdal Dillioğlugil
İbrahim Çevik
author_sort Oğuz Özden Cebeci
collection DOAJ
description Objective:Residual stone fragments remain a challenging topic for urologists following retrograde intrarenal surgery (RIRS). This study aimed to investigate the effectiveness of second-look flexible ureteroscopy (URS) to achieve a true stone-free status and decrease stone-related events.Materials and Methods:The study included 176 consecutive patients treated with RIRS for kidney stones between October 2013 and December 2017. Patients were divided into two groups. Group 1 included patients who underwent only one session of RIRS (n=51) and group 2 included patients who undergo a second-look flexible URS after RIRS (n=125). Both groups were compared for stone-free rates and potential risk factors associated with stone-related events. Stone-related events were defined as urinary infection, renal colic, stone enlargement, and any additional intervention with shock wave lithotripsy or reoperation.Results:Stone-free rate after RIRS for groups 1 and 2 were 37.25% (n=19/51) and 40.8% (n=51/125), respectively. The stone-free rates improved to 93.6% (n=117/125) in group 2 after the second-look flexible URS. The multivariable analysis revealed that type of intervention, stone size, and body mass index were independent prognostic factors for stone-related events. When group 2 was taken as a reference, the odds ratio for stone-related events was 8.48 (95% confidence interval: 2.95-24.42) in group 1.Conclusion:Second-look flexible ureterorenoscopy increased the stone-free rates and diminished the number of stone-related events. We argue that performing second-look flexible ureterorenoscopy in the early period following RIRS in the presence or suspicion of residual stone fragments provides better treatment results.
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spelling doaj.art-0bd725932d404effb6dacf9f50e5735b2023-02-15T16:16:02ZengGalenos YayineviJournal of Urological Surgery2148-95802022-03-0191404610.4274/jus.galenos.2021.2021.009213049054Effectiveness of Second-look Flexible Ureteroscopy to Achieve A True Stone-Free Status in Retrograde Intrarenal SurgeryOğuz Özden Cebeci0Tayyar Alp Özkan1Mustafa Savaş Yalçın2Özdal Dillioğlugil3İbrahim Çevik4 University of Health Sciences Turkiye, Kocaeli Derince Training and Research Hospital, Clinic of Urology, Kocaeli, Turkiye Acıbadem Kocaeli Hospital, Clinic of Urology, Kocaeli, Turkiye Private Dr. Nazif Bağrıaçık Kadıköy Hospital, Clinic of Urology, İstanbul, Turkiye Kocaeli University Faculty of Medicine, Department of Urology, Kocaeli, Turkiye Private Dr. Nazif Bağrıaçık Kadıköy Hospital, Clinic of Urology, İstanbul, Turkiye Objective:Residual stone fragments remain a challenging topic for urologists following retrograde intrarenal surgery (RIRS). This study aimed to investigate the effectiveness of second-look flexible ureteroscopy (URS) to achieve a true stone-free status and decrease stone-related events.Materials and Methods:The study included 176 consecutive patients treated with RIRS for kidney stones between October 2013 and December 2017. Patients were divided into two groups. Group 1 included patients who underwent only one session of RIRS (n=51) and group 2 included patients who undergo a second-look flexible URS after RIRS (n=125). Both groups were compared for stone-free rates and potential risk factors associated with stone-related events. Stone-related events were defined as urinary infection, renal colic, stone enlargement, and any additional intervention with shock wave lithotripsy or reoperation.Results:Stone-free rate after RIRS for groups 1 and 2 were 37.25% (n=19/51) and 40.8% (n=51/125), respectively. The stone-free rates improved to 93.6% (n=117/125) in group 2 after the second-look flexible URS. The multivariable analysis revealed that type of intervention, stone size, and body mass index were independent prognostic factors for stone-related events. When group 2 was taken as a reference, the odds ratio for stone-related events was 8.48 (95% confidence interval: 2.95-24.42) in group 1.Conclusion:Second-look flexible ureterorenoscopy increased the stone-free rates and diminished the number of stone-related events. We argue that performing second-look flexible ureterorenoscopy in the early period following RIRS in the presence or suspicion of residual stone fragments provides better treatment results. http://jurolsurgery.org/archives/archive-detail/article-preview/effectiveness-of-second-look-flexible-ureteroscopy/51029 retrograde intrarenal surgerysecond-look flexible ureteroscopystone-free rateresidual stone fragmentsstone-related event
spellingShingle Oğuz Özden Cebeci
Tayyar Alp Özkan
Mustafa Savaş Yalçın
Özdal Dillioğlugil
İbrahim Çevik
Effectiveness of Second-look Flexible Ureteroscopy to Achieve A True Stone-Free Status in Retrograde Intrarenal Surgery
Journal of Urological Surgery
retrograde intrarenal surgery
second-look flexible ureteroscopy
stone-free rate
residual stone fragments
stone-related event
title Effectiveness of Second-look Flexible Ureteroscopy to Achieve A True Stone-Free Status in Retrograde Intrarenal Surgery
title_full Effectiveness of Second-look Flexible Ureteroscopy to Achieve A True Stone-Free Status in Retrograde Intrarenal Surgery
title_fullStr Effectiveness of Second-look Flexible Ureteroscopy to Achieve A True Stone-Free Status in Retrograde Intrarenal Surgery
title_full_unstemmed Effectiveness of Second-look Flexible Ureteroscopy to Achieve A True Stone-Free Status in Retrograde Intrarenal Surgery
title_short Effectiveness of Second-look Flexible Ureteroscopy to Achieve A True Stone-Free Status in Retrograde Intrarenal Surgery
title_sort effectiveness of second look flexible ureteroscopy to achieve a true stone free status in retrograde intrarenal surgery
topic retrograde intrarenal surgery
second-look flexible ureteroscopy
stone-free rate
residual stone fragments
stone-related event
url http://jurolsurgery.org/archives/archive-detail/article-preview/effectiveness-of-second-look-flexible-ureteroscopy/51029
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