Histone deacetylases control neurogenesis in embryonic brain by inhibition of BMP2/4 signaling.

BACKGROUND: Histone-modifying enzymes are essential for a wide variety of cellular processes dependent upon changes in gene expression. Histone deacetylases (HDACs) lead to the compaction of chromatin and subsequent silencing of gene transcription, and they have recently been implicated in a diversi...

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Detalles Bibliográficos
Main Authors: Maya Shakèd, Kathrin Weissmüller, Hanno Svoboda, Peter Hortschansky, Norikazu Nishino, Stefan Wölfl, Kerry L Tucker
Formato: Artigo
Idioma:English
Publicado: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC2441862?pdf=render