Toxic Activity, Molecular Modeling and Docking Simulations of Bacillus thuringiensis Cry11 Toxin Variants Obtained via DNA Shuffling

Toxic Activity, Molecular Modeling and Docking Simulations of Bacillus thuringiensis Cry11 Toxin Variants Obtained via DNA Shuffling

The Cry11 family belongs to a large group of δ-endotoxins that share three distinct structural domains. Among the dipteran-active toxins referred to as three-domain Cry11 toxins, the Cry11Aa protein from Bacillus thuringiensis subsp. israelensis (Bti) has been the most extensively studied. Despite t...

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Bibliographic Details
Main Authors: Alvaro Mauricio Florez, Miguel Orlando Suarez-Barrera, Gloria M. Morales, Karen Viviana Rivera, Sergio Orduz, Rodrigo Ochoa, Diego Guerra, Carlos Muskus
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Microbiology
Subjects:
Bacillus thuringiensis
Cry11
DNA shuffling
docking
Aedes aegypti
Culex quinquefasciatus
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02461/full

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