Occupational Hearing Loss Associated with the Combined Exposure of Solvents and Noise: A Systematic Review and Meta-Analysis
To analyze the predominant frequencies of hearing threshold shift and the prevalence of hearing loss related to the co-exposure to noise and solvents. A systematic review and meta-analysis were performed by retrieving published articles from Web of Science, PubMed, Scopus, Embase, and ProQuest until...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-10-01
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| Series: | Safety |
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| Online Access: | https://www.mdpi.com/2313-576X/9/4/71 |
| _version_ | 1797379401884631040 |
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| author | Jia Ren Hongwei Xie Yong Hu Yu Hong Hua Zou Xiangjing Gao |
| author_facet | Jia Ren Hongwei Xie Yong Hu Yu Hong Hua Zou Xiangjing Gao |
| author_sort | Jia Ren |
| collection | DOAJ |
| description | To analyze the predominant frequencies of hearing threshold shift and the prevalence of hearing loss related to the co-exposure to noise and solvents. A systematic review and meta-analysis were performed by retrieving published articles from Web of Science, PubMed, Scopus, Embase, and ProQuest until July 2023. Data were extracted in line with the Cochrane Collaboration Handbook, and the Newcastle-Ottawa Scale and Agency for Healthcare Research and Quality were used to assess the studies’ quality. The meta-analysis was used to estimate the odds ratios (ORs) with 95% confidence interval (CI). I<sup>2</sup> and Q statistics were used to prove the heterogeneity. A total of 22 selected studies (9948 workers), six cohort studies and 16 cross-sectional studies were included. The results revealed that 43.7%, 41.3%, and 53.6% of the participants presented with hearing loss due to noise exposure, solvent exposure, and combined exposure to noise and solvent, respectively. The workers exposed to both noise and solvents had a higher risk of hearing loss than those exposed to noise (overall weighted odds ratio [OR]: 1.76) or solvents (overall-weighted OR: 2.02) alone. The poorer hearing threshold in the combined noise and solvents exposure group was mainly at high frequencies (3, 4, 6, and 8 kHz), with a peak of 29.47 dB HL at 6 kHz. The noise-exposed group’s peak hearing threshold was 28.87 dB HL at 4 kHz. The peak hearing threshold of the solvent-exposed group was 28.65 dB HL at 6 kHz. The workers exposed to noise and solvent simultaneously had a higher prevalence of hearing loss than those exposed to solvents. Co-exposure to noise and solvents increases the odds of hearing loss. The dominant hearing threshold changes occurred at 3, 4, 6, and 8 kHz, and the peak value appeared at 6 kHz in workers co-exposed to noise and solvents. |
| first_indexed | 2024-03-08T20:22:42Z |
| format | Article |
| id | doaj.art-0be1ceb3fa9641f8833855f7d4262993 |
| institution | Directory Open Access Journal |
| issn | 2313-576X |
| language | English |
| last_indexed | 2024-03-08T20:22:42Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Safety |
| spelling | doaj.art-0be1ceb3fa9641f8833855f7d42629932023-12-22T14:39:45ZengMDPI AGSafety2313-576X2023-10-01947110.3390/safety9040071Occupational Hearing Loss Associated with the Combined Exposure of Solvents and Noise: A Systematic Review and Meta-AnalysisJia Ren0Hongwei Xie1Yong Hu2Yu Hong3Hua Zou4Xiangjing Gao5Department of Occupational Health and Radiation Protection, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, ChinaDepartment of Occupational Health and Radiation Protection, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, ChinaDepartment of Occupational Health and Radiation Protection, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, ChinaDepartment of Public Health, Hangzhou Normal University, Hangzhou 310030, ChinaDepartment of Occupational Health and Radiation Protection, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, ChinaDepartment of Occupational Health and Radiation Protection, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, ChinaTo analyze the predominant frequencies of hearing threshold shift and the prevalence of hearing loss related to the co-exposure to noise and solvents. A systematic review and meta-analysis were performed by retrieving published articles from Web of Science, PubMed, Scopus, Embase, and ProQuest until July 2023. Data were extracted in line with the Cochrane Collaboration Handbook, and the Newcastle-Ottawa Scale and Agency for Healthcare Research and Quality were used to assess the studies’ quality. The meta-analysis was used to estimate the odds ratios (ORs) with 95% confidence interval (CI). I<sup>2</sup> and Q statistics were used to prove the heterogeneity. A total of 22 selected studies (9948 workers), six cohort studies and 16 cross-sectional studies were included. The results revealed that 43.7%, 41.3%, and 53.6% of the participants presented with hearing loss due to noise exposure, solvent exposure, and combined exposure to noise and solvent, respectively. The workers exposed to both noise and solvents had a higher risk of hearing loss than those exposed to noise (overall weighted odds ratio [OR]: 1.76) or solvents (overall-weighted OR: 2.02) alone. The poorer hearing threshold in the combined noise and solvents exposure group was mainly at high frequencies (3, 4, 6, and 8 kHz), with a peak of 29.47 dB HL at 6 kHz. The noise-exposed group’s peak hearing threshold was 28.87 dB HL at 4 kHz. The peak hearing threshold of the solvent-exposed group was 28.65 dB HL at 6 kHz. The workers exposed to noise and solvent simultaneously had a higher prevalence of hearing loss than those exposed to solvents. Co-exposure to noise and solvents increases the odds of hearing loss. The dominant hearing threshold changes occurred at 3, 4, 6, and 8 kHz, and the peak value appeared at 6 kHz in workers co-exposed to noise and solvents.https://www.mdpi.com/2313-576X/9/4/71hearing losscombined exposureototoxic solventsnoise effectsoccupational exposure |
| spellingShingle | Jia Ren Hongwei Xie Yong Hu Yu Hong Hua Zou Xiangjing Gao Occupational Hearing Loss Associated with the Combined Exposure of Solvents and Noise: A Systematic Review and Meta-Analysis Safety hearing loss combined exposure ototoxic solvents noise effects occupational exposure |
| title | Occupational Hearing Loss Associated with the Combined Exposure of Solvents and Noise: A Systematic Review and Meta-Analysis |
| title_full | Occupational Hearing Loss Associated with the Combined Exposure of Solvents and Noise: A Systematic Review and Meta-Analysis |
| title_fullStr | Occupational Hearing Loss Associated with the Combined Exposure of Solvents and Noise: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Occupational Hearing Loss Associated with the Combined Exposure of Solvents and Noise: A Systematic Review and Meta-Analysis |
| title_short | Occupational Hearing Loss Associated with the Combined Exposure of Solvents and Noise: A Systematic Review and Meta-Analysis |
| title_sort | occupational hearing loss associated with the combined exposure of solvents and noise a systematic review and meta analysis |
| topic | hearing loss combined exposure ototoxic solvents noise effects occupational exposure |
| url | https://www.mdpi.com/2313-576X/9/4/71 |
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