PREVENTION AND TREATMENT OF HAEMOPHILIC ARTHROPATHY

Background. The main clinical manifestations of hemophilia are spontaneous hemarthrosis and haemophilic arthropathy. Currently (since 2009) two hemostatic therapy regimens are employed in Belarus – «on demand» and prophylactic ones. The purpose of this research was to clarify the influence of dif...

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Main Authors: Shpileuski I., Volkova L., Maluk B.
Format: Article
Language:Belarusian
Published: Grodno State Medical University 2019-11-01
Series:Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta
Subjects:
Online Access:http://journal-grsmu.by/index.php/ojs/article/view/2451
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author Shpileuski I.
Volkova L.
Maluk B.
author_facet Shpileuski I.
Volkova L.
Maluk B.
author_sort Shpileuski I.
collection DOAJ
description Background. The main clinical manifestations of hemophilia are spontaneous hemarthrosis and haemophilic arthropathy. Currently (since 2009) two hemostatic therapy regimens are employed in Belarus – «on demand» and prophylactic ones. The purpose of this research was to clarify the influence of different types of hemostatic therapy on the development of hemophilic arthropathy and to determine the effectiveness of chemical synoviorthesis and total knee replacement (TKR). Material and methods. A retrospective analysis of the therapy and its results in 87 patients with severe hemophilia treated at the Belarusian Research and Practical Center of Traumatology and Orthopedic Surgery and Belarusian Research Center for Pediatric Oncology, Hematology and Immunology during 2009-2018 years was performed. Results. The obtained findings showed that prophylactic hemostatic therapy prevented the development of haemophilic arthropathy. In the patients treated "on demand" the progression of haemophilic arthropathy could be slowed down by chemical synoviorthesis; in the cases of its later stages the operation of choice was TKR.
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spelling doaj.art-0be443795912442a8cc67738a7b4a4502022-12-22T03:34:17ZbelGrodno State Medical UniversityŽurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta2221-87852413-01092019-11-0117550651110.25298/2221-8785-2019-17-5-506-511PREVENTION AND TREATMENT OF HAEMOPHILIC ARTHROPATHYShpileuski I.0Volkova L.1Maluk B.2Belarusian Research and Practical Center of Traumatology and Orthopedic SurgeryBelarusian Medical Academy of Postgraduate EducationBelarusian Research and Practical Center of Traumatology and Orthopedic SurgeryBackground. The main clinical manifestations of hemophilia are spontaneous hemarthrosis and haemophilic arthropathy. Currently (since 2009) two hemostatic therapy regimens are employed in Belarus – «on demand» and prophylactic ones. The purpose of this research was to clarify the influence of different types of hemostatic therapy on the development of hemophilic arthropathy and to determine the effectiveness of chemical synoviorthesis and total knee replacement (TKR). Material and methods. A retrospective analysis of the therapy and its results in 87 patients with severe hemophilia treated at the Belarusian Research and Practical Center of Traumatology and Orthopedic Surgery and Belarusian Research Center for Pediatric Oncology, Hematology and Immunology during 2009-2018 years was performed. Results. The obtained findings showed that prophylactic hemostatic therapy prevented the development of haemophilic arthropathy. In the patients treated "on demand" the progression of haemophilic arthropathy could be slowed down by chemical synoviorthesis; in the cases of its later stages the operation of choice was TKR.http://journal-grsmu.by/index.php/ojs/article/view/2451haemophiliahaemophilic arthropathychemical synoviorthesistotal knee replacement
spellingShingle Shpileuski I.
Volkova L.
Maluk B.
PREVENTION AND TREATMENT OF HAEMOPHILIC ARTHROPATHY
Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta
haemophilia
haemophilic arthropathy
chemical synoviorthesis
total knee replacement
title PREVENTION AND TREATMENT OF HAEMOPHILIC ARTHROPATHY
title_full PREVENTION AND TREATMENT OF HAEMOPHILIC ARTHROPATHY
title_fullStr PREVENTION AND TREATMENT OF HAEMOPHILIC ARTHROPATHY
title_full_unstemmed PREVENTION AND TREATMENT OF HAEMOPHILIC ARTHROPATHY
title_short PREVENTION AND TREATMENT OF HAEMOPHILIC ARTHROPATHY
title_sort prevention and treatment of haemophilic arthropathy
topic haemophilia
haemophilic arthropathy
chemical synoviorthesis
total knee replacement
url http://journal-grsmu.by/index.php/ojs/article/view/2451
work_keys_str_mv AT shpileuskii preventionandtreatmentofhaemophilicarthropathy
AT volkoval preventionandtreatmentofhaemophilicarthropathy
AT malukb preventionandtreatmentofhaemophilicarthropathy