Factors affecting the intention of COVID-19 vaccination in Korean patients with myasthenia gravis: A survey-based study
ObjectiveTo investigate the intention of coronavirus disease 2019 (COVID-19) vaccination in Korean patients with myasthenia gravis (MG) and to determine the factors that influence their attitude toward COVID-19 vaccination.Materials and methodsWe conducted a questionnaire survey of 160 Korean patien...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-08-01
|
| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.847873/full |
| _version_ | 1811315694991572992 |
|---|---|
| author | Sooyoung Kim Seong Ho Jeong Ha Young Shin Seung Woo Kim |
| author_facet | Sooyoung Kim Seong Ho Jeong Ha Young Shin Seung Woo Kim |
| author_sort | Sooyoung Kim |
| collection | DOAJ |
| description | ObjectiveTo investigate the intention of coronavirus disease 2019 (COVID-19) vaccination in Korean patients with myasthenia gravis (MG) and to determine the factors that influence their attitude toward COVID-19 vaccination.Materials and methodsWe conducted a questionnaire survey of 160 Korean patients with MG. The questionnaire consisted of five categories, including vaccination status, willingness to get vaccinated, general concerns over vaccination, impact of MG diagnosis on vaccination decision, and MG-specific concerns over vaccination. The responses were rated from 1 (no intention or influence) to 5 (significant intention or influence). We compared the clinical factors between patients willing to get vaccinated (willing group) and those who were neutral or unwilling (hesitant group).ResultsThe average score of willingness to get vaccinated was 4.1 ± 1.2 (Likert score, 1–5). The hesitant group demonstrated higher proportions of women, patients with MG Foundation of America (MGFA) classification ≥III at nadir, and those who had experienced myasthenic crisis than the willing group (women, p = 0.027; MGFA classification≥III, p = 0.018; myasthenic crisis, p = 0.027). Scores for the willingness to get vaccinated (Likert score, 1–5) were negatively correlated with the MGFA classification at nadir (r = −0.235, p = 0.003), degree of general concern about vaccination (r = −0.362, p < 0.001), and impact of MG diagnosis on vaccination decision (r = −0.365, p < 0.001). In the path analysis, the MGFA classification at nadir was negatively associated with the willingness to get vaccinated by increasing the impact of MG diagnosis on vaccination decision.ConclusionMG diagnosis, maximum disease severity, and general concerns about vaccination influenced the intention to get vaccinated. |
| first_indexed | 2024-04-13T11:34:46Z |
| format | Article |
| id | doaj.art-0beae3283c3a4a65bfe40dfa921d0a94 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-13T11:34:46Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-0beae3283c3a4a65bfe40dfa921d0a942022-12-22T02:48:28ZengFrontiers Media S.A.Frontiers in Neurology1664-22952022-08-011310.3389/fneur.2022.847873847873Factors affecting the intention of COVID-19 vaccination in Korean patients with myasthenia gravis: A survey-based studySooyoung Kim0Seong Ho Jeong1Ha Young Shin2Seung Woo Kim3Department of Neurology, Chungnam National University Hospital, Daejeon, South KoreaDepartment of Neurology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, South KoreaDepartment of Neurology, Yonsei University College of Medicine, Seoul, South KoreaDepartment of Neurology, Yonsei University College of Medicine, Seoul, South KoreaObjectiveTo investigate the intention of coronavirus disease 2019 (COVID-19) vaccination in Korean patients with myasthenia gravis (MG) and to determine the factors that influence their attitude toward COVID-19 vaccination.Materials and methodsWe conducted a questionnaire survey of 160 Korean patients with MG. The questionnaire consisted of five categories, including vaccination status, willingness to get vaccinated, general concerns over vaccination, impact of MG diagnosis on vaccination decision, and MG-specific concerns over vaccination. The responses were rated from 1 (no intention or influence) to 5 (significant intention or influence). We compared the clinical factors between patients willing to get vaccinated (willing group) and those who were neutral or unwilling (hesitant group).ResultsThe average score of willingness to get vaccinated was 4.1 ± 1.2 (Likert score, 1–5). The hesitant group demonstrated higher proportions of women, patients with MG Foundation of America (MGFA) classification ≥III at nadir, and those who had experienced myasthenic crisis than the willing group (women, p = 0.027; MGFA classification≥III, p = 0.018; myasthenic crisis, p = 0.027). Scores for the willingness to get vaccinated (Likert score, 1–5) were negatively correlated with the MGFA classification at nadir (r = −0.235, p = 0.003), degree of general concern about vaccination (r = −0.362, p < 0.001), and impact of MG diagnosis on vaccination decision (r = −0.365, p < 0.001). In the path analysis, the MGFA classification at nadir was negatively associated with the willingness to get vaccinated by increasing the impact of MG diagnosis on vaccination decision.ConclusionMG diagnosis, maximum disease severity, and general concerns about vaccination influenced the intention to get vaccinated.https://www.frontiersin.org/articles/10.3389/fneur.2022.847873/fullcoronavirus disease 2019COVID-19myasthenia gravisquestionnaire surveyvaccination |
| spellingShingle | Sooyoung Kim Seong Ho Jeong Ha Young Shin Seung Woo Kim Factors affecting the intention of COVID-19 vaccination in Korean patients with myasthenia gravis: A survey-based study Frontiers in Neurology coronavirus disease 2019 COVID-19 myasthenia gravis questionnaire survey vaccination |
| title | Factors affecting the intention of COVID-19 vaccination in Korean patients with myasthenia gravis: A survey-based study |
| title_full | Factors affecting the intention of COVID-19 vaccination in Korean patients with myasthenia gravis: A survey-based study |
| title_fullStr | Factors affecting the intention of COVID-19 vaccination in Korean patients with myasthenia gravis: A survey-based study |
| title_full_unstemmed | Factors affecting the intention of COVID-19 vaccination in Korean patients with myasthenia gravis: A survey-based study |
| title_short | Factors affecting the intention of COVID-19 vaccination in Korean patients with myasthenia gravis: A survey-based study |
| title_sort | factors affecting the intention of covid 19 vaccination in korean patients with myasthenia gravis a survey based study |
| topic | coronavirus disease 2019 COVID-19 myasthenia gravis questionnaire survey vaccination |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2022.847873/full |
| work_keys_str_mv | AT sooyoungkim factorsaffectingtheintentionofcovid19vaccinationinkoreanpatientswithmyastheniagravisasurveybasedstudy AT seonghojeong factorsaffectingtheintentionofcovid19vaccinationinkoreanpatientswithmyastheniagravisasurveybasedstudy AT hayoungshin factorsaffectingtheintentionofcovid19vaccinationinkoreanpatientswithmyastheniagravisasurveybasedstudy AT seungwookim factorsaffectingtheintentionofcovid19vaccinationinkoreanpatientswithmyastheniagravisasurveybasedstudy |