Two New Dexpanthenol-Containing Wash Gels: Skin Hydration, Barrier Function, and Cosmetic Performance Upon Single and Repeated Usage in Subjects with Dry Skin
Two novel body/face wash gels enriched with emollient ingredients (including dexpanthenol) were developed for the daily care of dry skin. Two similarly designed 2-week studies (N = 42 each) were conducted to assess the biophysical and cosmetic performance of each of the new wash gels in healthy adul...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Cosmetics |
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| Online Access: | https://www.mdpi.com/2079-9284/8/2/44 |
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| author | Ana Barrionuevo-Gonzalez Sonja Trapp Raffaella de Salvo Rozalia Olsavszky Elena Alina Nanu Ioan Dopcea Veronica Dumitru Hans Stettler |
| author_facet | Ana Barrionuevo-Gonzalez Sonja Trapp Raffaella de Salvo Rozalia Olsavszky Elena Alina Nanu Ioan Dopcea Veronica Dumitru Hans Stettler |
| author_sort | Ana Barrionuevo-Gonzalez |
| collection | DOAJ |
| description | Two novel body/face wash gels enriched with emollient ingredients (including dexpanthenol) were developed for the daily care of dry skin. Two similarly designed 2-week studies (N = 42 each) were conducted to assess the biophysical and cosmetic performance of each of the new wash gels in healthy adults with dry skin. Instrumental measurements quantified the effects of the wash gels on stratum corneum (SC) hydration and transepidermal water loss (TEWL) (with and without a previous sodium lauryl sulfate (SLS) challenge) after single and repeated usage. Following single and repeated applications of the face wash gel to facial skin, as well as to dry SLS-undamaged and SLS-damaged skin of the forearm, skin hydration significantly increased. Similarly, after single and repeated usage of the body wash gel to dry SLS-undamaged and SLS-damaged skin of the forearm, skin moisturization increased significantly from baseline; comparisons with control areas provided inconsistent results for SLS-undamaged skin. No effects on TEWL were observed for either product. Both wash gels were well tolerated and the cosmetic performances were appreciated by the subjects. The study results suggest that daily use of the new wash gels was associated with significant skin-moisturizing effects without adversely affecting skin barrier function and repair. |
| first_indexed | 2024-03-10T10:47:29Z |
| format | Article |
| id | doaj.art-0beb9399034b4346ba36b2b2dee3308f |
| institution | Directory Open Access Journal |
| issn | 2079-9284 |
| language | English |
| last_indexed | 2024-03-10T10:47:29Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cosmetics |
| spelling | doaj.art-0beb9399034b4346ba36b2b2dee3308f2023-11-21T22:25:35ZengMDPI AGCosmetics2079-92842021-06-01824410.3390/cosmetics8020044Two New Dexpanthenol-Containing Wash Gels: Skin Hydration, Barrier Function, and Cosmetic Performance Upon Single and Repeated Usage in Subjects with Dry SkinAna Barrionuevo-Gonzalez0Sonja Trapp1Raffaella de Salvo2Rozalia Olsavszky3Elena Alina Nanu4Ioan Dopcea5Veronica Dumitru6Hans Stettler7Bayer Hispania, S.L., 08970 Sant Joan Despí, SpainBayer Consumer Care AG, 4002 Basel, SwitzerlandBayer Consumer Care AG, 4002 Basel, SwitzerlandEurofins Evic Product Testing Romania SRL, 040256 Bucharest, RomaniaEurofins Evic Product Testing Romania SRL, 040256 Bucharest, RomaniaEurofins Evic Product Testing Romania SRL, 040256 Bucharest, RomaniaEurofins Evic Product Testing Romania SRL, 040256 Bucharest, RomaniaBayer Consumer Care AG, 4002 Basel, SwitzerlandTwo novel body/face wash gels enriched with emollient ingredients (including dexpanthenol) were developed for the daily care of dry skin. Two similarly designed 2-week studies (N = 42 each) were conducted to assess the biophysical and cosmetic performance of each of the new wash gels in healthy adults with dry skin. Instrumental measurements quantified the effects of the wash gels on stratum corneum (SC) hydration and transepidermal water loss (TEWL) (with and without a previous sodium lauryl sulfate (SLS) challenge) after single and repeated usage. Following single and repeated applications of the face wash gel to facial skin, as well as to dry SLS-undamaged and SLS-damaged skin of the forearm, skin hydration significantly increased. Similarly, after single and repeated usage of the body wash gel to dry SLS-undamaged and SLS-damaged skin of the forearm, skin moisturization increased significantly from baseline; comparisons with control areas provided inconsistent results for SLS-undamaged skin. No effects on TEWL were observed for either product. Both wash gels were well tolerated and the cosmetic performances were appreciated by the subjects. The study results suggest that daily use of the new wash gels was associated with significant skin-moisturizing effects without adversely affecting skin barrier function and repair.https://www.mdpi.com/2079-9284/8/2/44body washcleanserdexpanthenoldry skinface washmoisturization |
| spellingShingle | Ana Barrionuevo-Gonzalez Sonja Trapp Raffaella de Salvo Rozalia Olsavszky Elena Alina Nanu Ioan Dopcea Veronica Dumitru Hans Stettler Two New Dexpanthenol-Containing Wash Gels: Skin Hydration, Barrier Function, and Cosmetic Performance Upon Single and Repeated Usage in Subjects with Dry Skin Cosmetics body wash cleanser dexpanthenol dry skin face wash moisturization |
| title | Two New Dexpanthenol-Containing Wash Gels: Skin Hydration, Barrier Function, and Cosmetic Performance Upon Single and Repeated Usage in Subjects with Dry Skin |
| title_full | Two New Dexpanthenol-Containing Wash Gels: Skin Hydration, Barrier Function, and Cosmetic Performance Upon Single and Repeated Usage in Subjects with Dry Skin |
| title_fullStr | Two New Dexpanthenol-Containing Wash Gels: Skin Hydration, Barrier Function, and Cosmetic Performance Upon Single and Repeated Usage in Subjects with Dry Skin |
| title_full_unstemmed | Two New Dexpanthenol-Containing Wash Gels: Skin Hydration, Barrier Function, and Cosmetic Performance Upon Single and Repeated Usage in Subjects with Dry Skin |
| title_short | Two New Dexpanthenol-Containing Wash Gels: Skin Hydration, Barrier Function, and Cosmetic Performance Upon Single and Repeated Usage in Subjects with Dry Skin |
| title_sort | two new dexpanthenol containing wash gels skin hydration barrier function and cosmetic performance upon single and repeated usage in subjects with dry skin |
| topic | body wash cleanser dexpanthenol dry skin face wash moisturization |
| url | https://www.mdpi.com/2079-9284/8/2/44 |
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