Cis,exo-1,2,3,4,4a,13b-hexahydro-1,4-methano-5-isopropoxy-9H-tribenzo[b,f]azepine
The title compound—cis,exo-1,2,3,4,4a,13b-hexahydro-1,4-methano-5-isopropoxy-9H-tribenzo[b,f]azepine—was synthesized in 83% isolated yield by a palladium-catalyzed one-pot strategy from 1-iodo-2-isopropoxybenzene and ortho-bromoaniline. The azepine derivative was fully characterized (FT-IR, MS, 1H a...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-03-01
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| Series: | Molbank |
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| Online Access: | http://www.mdpi.com/1422-8599/2018/1/M988 |
| _version_ | 1818441405453828096 |
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| author | Alessandra Casnati Elena Motti Nicola Della Ca’ |
| author_facet | Alessandra Casnati Elena Motti Nicola Della Ca’ |
| author_sort | Alessandra Casnati |
| collection | DOAJ |
| description | The title compound—cis,exo-1,2,3,4,4a,13b-hexahydro-1,4-methano-5-isopropoxy-9H-tribenzo[b,f]azepine—was synthesized in 83% isolated yield by a palladium-catalyzed one-pot strategy from 1-iodo-2-isopropoxybenzene and ortho-bromoaniline. The azepine derivative was fully characterized (FT-IR, MS, 1H and 13C-NMR, elemental analysis) and all proton and carbon signals have been completely assigned by 2D NMR experiments. |
| first_indexed | 2024-12-14T18:27:44Z |
| format | Article |
| id | doaj.art-0bedfceae6b54e97b8cde5e02fd8c136 |
| institution | Directory Open Access Journal |
| issn | 1422-8599 |
| language | English |
| last_indexed | 2024-12-14T18:27:44Z |
| publishDate | 2018-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molbank |
| spelling | doaj.art-0bedfceae6b54e97b8cde5e02fd8c1362022-12-21T22:51:53ZengMDPI AGMolbank1422-85992018-03-0120181M98810.3390/M988M988Cis,exo-1,2,3,4,4a,13b-hexahydro-1,4-methano-5-isopropoxy-9H-tribenzo[b,f]azepineAlessandra Casnati0Elena Motti1Nicola Della Ca’2Department of Chemistry, Life Sciences and Environmental Sustainability (SCVSA), University of Parma, Parco Area delle Scienze 17/A, 43124 Parma, ItalyDepartment of Chemistry, Life Sciences and Environmental Sustainability (SCVSA), University of Parma, Parco Area delle Scienze 17/A, 43124 Parma, ItalyDepartment of Chemistry, Life Sciences and Environmental Sustainability (SCVSA), University of Parma, Parco Area delle Scienze 17/A, 43124 Parma, ItalyThe title compound—cis,exo-1,2,3,4,4a,13b-hexahydro-1,4-methano-5-isopropoxy-9H-tribenzo[b,f]azepine—was synthesized in 83% isolated yield by a palladium-catalyzed one-pot strategy from 1-iodo-2-isopropoxybenzene and ortho-bromoaniline. The azepine derivative was fully characterized (FT-IR, MS, 1H and 13C-NMR, elemental analysis) and all proton and carbon signals have been completely assigned by 2D NMR experiments.http://www.mdpi.com/1422-8599/2018/1/M988palladiumnorbornenebenzo[b,f]azepineC-C and C-N couplingsmulticomponentone-pot reaction |
| spellingShingle | Alessandra Casnati Elena Motti Nicola Della Ca’ Cis,exo-1,2,3,4,4a,13b-hexahydro-1,4-methano-5-isopropoxy-9H-tribenzo[b,f]azepine Molbank palladium norbornene benzo[b,f]azepine C-C and C-N couplings multicomponent one-pot reaction |
| title | Cis,exo-1,2,3,4,4a,13b-hexahydro-1,4-methano-5-isopropoxy-9H-tribenzo[b,f]azepine |
| title_full | Cis,exo-1,2,3,4,4a,13b-hexahydro-1,4-methano-5-isopropoxy-9H-tribenzo[b,f]azepine |
| title_fullStr | Cis,exo-1,2,3,4,4a,13b-hexahydro-1,4-methano-5-isopropoxy-9H-tribenzo[b,f]azepine |
| title_full_unstemmed | Cis,exo-1,2,3,4,4a,13b-hexahydro-1,4-methano-5-isopropoxy-9H-tribenzo[b,f]azepine |
| title_short | Cis,exo-1,2,3,4,4a,13b-hexahydro-1,4-methano-5-isopropoxy-9H-tribenzo[b,f]azepine |
| title_sort | cis exo 1 2 3 4 4a 13b hexahydro 1 4 methano 5 isopropoxy 9h tribenzo b f azepine |
| topic | palladium norbornene benzo[b,f]azepine C-C and C-N couplings multicomponent one-pot reaction |
| url | http://www.mdpi.com/1422-8599/2018/1/M988 |
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