Sequestration of 9-Hydroxystearic Acid in FAHFA (Fatty Acid Esters of Hydroxy Fatty Acids) as a Protective Mechanism for Colon Carcinoma Cells to Avoid Apoptotic Cell Death

Hydroxy fatty acids are known to cause cell cycle arrest and apoptosis. The best studied of them, 9-hydroxystearic acid (9-HSA), induces apoptosis in cell lines by acting through mechanisms involving different targets. Using mass spectrometry-based lipidomic approaches, we show in this study that 9-...

Full description

Bibliographic Details
Main Authors: Juan P. Rodríguez, Carlos Guijas, Alma M. Astudillo, Julio M. Rubio, María A. Balboa, Jesús Balsinde
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/4/524