Using population selection and sequencing to characterize natural variation of starvation resistance in Caenorhabditis elegans
Starvation resistance is important to disease and fitness, but the genetic basis of its natural variation is unknown. Uncovering the genetic basis of complex, quantitative traits such as starvation resistance is technically challenging. We developed a synthetic-population (re)sequencing approach usi...
Main Authors: | Amy K Webster, Rojin Chitrakar, Maya Powell, Jingxian Chen, Kinsey Fisher, Robyn E Tanny, Lewis Stevens, Kathryn Evans, Angela Wei, Igor Antoshechkin, Erik C Andersen, L Ryan Baugh |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2022-06-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/80204 |
Similar Items
-
Population Selection and Sequencing of Caenorhabditis elegans Wild Isolates Identifies a Region on Chromosome III Affecting Starvation Resistance
by: Amy K. Webster, et al.
Published: (2019-10-01) -
Insights Into the Hypometabolic Stage Caused by Prolonged Starvation in L4-Adult Caenorhabditis elegans Hermaphrodites
by: E. Carranza-García, et al.
Published: (2020-02-01) -
Reactivation of RNA metabolism underlies somatic restoration after adult reproductive diapause in C. elegans
by: Nikolay Burnaevskiy, et al.
Published: (2018-08-01) -
daf-16/FoxO promotes gluconeogenesis and trehalose synthesis during starvation to support survival
by: Jonathan D Hibshman, et al.
Published: (2017-10-01) -
Decoding lifespan secrets: the role of the gonad in Caenorhabditis elegans aging
by: Andre Pires da Silva, et al.
Published: (2024-03-01)