Rutin Inhibits Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation by Inducing Autophagy and Modulating PI3K/ATK Signaling

Rutin Inhibits Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation by Inducing Autophagy and Modulating PI3K/ATK Signaling

Atherosclerosis (AS) is one of the leading causes of death among the elderly, and is primarily caused by foam cell generation and macrophage inflammation. Rutin is an anti-inflammatory, anti-oxidant, anti-allergic, and antiviral flavonoid molecule, known to have anti-atherosclerotic and autophagy-in...

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Bibliographic Details
Main Authors: Ben Li, Yumeng Ji, Chenlong Yi, Xufeng Wang, Chaoyang Liu, Chufan Wang, Xiaohu Lu, Xiaohan Xu, Xiaowei Wang
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
rutin
atherosclerosis
RAW264.7
inflammation
autophagy
Online Access:https://www.mdpi.com/1420-3049/27/13/4201

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