Synthesis of Azulene Derivatives from 2<em>H</em>-Cyclohepta[<em>b</em>]furan-2-ones as Starting Materials: Their Reactivity and Properties
A variety of synthetic methods have been developed for azulene derivatives due to their potential applications in pharmaceuticals and organic materials. Particularly, 2<i>H</i>-cyclohepta[<i>b</i>]furan-2-one and its derivatives have been frequently used as promising precurso...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-10-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/22/19/10686 |
| Summary: | A variety of synthetic methods have been developed for azulene derivatives due to their potential applications in pharmaceuticals and organic materials. Particularly, 2<i>H</i>-cyclohepta[<i>b</i>]furan-2-one and its derivatives have been frequently used as promising precursors for the synthesis of azulenes. In this review, we describe the development of the synthesis of azulenes by the reaction of 2<i>H</i>-cyclohepta[<i>b</i>]furan-2-ones with olefins, active methylenes, enamines, and silyl enol ethers as well as their reactivity and properties. |
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| ISSN: | 1661-6596 1422-0067 |