Subtotal Nephrectomy Associated with a High-Phosphate Diet in Rats Mimics the Development of Calcified Aortic Valve Disease Associated with Chronic Renal Failure

Subtotal Nephrectomy Associated with a High-Phosphate Diet in Rats Mimics the Development of Calcified Aortic Valve Disease Associated with Chronic Renal Failure

<b>Introduction.</b> This study addressed the hypothesis that subtotal nephrectomy associated with a high-phosphorus diet (5/6Nx + P) in rats represents a suitable animal model to mimic the cardiovascular consequences of chronic kidney disease (CKD) including calcified aortic valve disea...

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Bibliographic Details
Main Authors: Hind Messaoudi, Thomas Levesque, Nicolas Perzo, Elodie Berg, Guillaume Feugray, Anaïs Dumesnil, Valéry Brunel, Dominique Guerrot, Hélène Eltchaninoff, Vincent Richard, Saïd Kamel, Eric Durand, Youssef Bennis, Jérémy Bellien
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Journal of Clinical Medicine
Subjects:
animal model
chronic kidney disease
cardiovascular complications
calcified aortic valve disease
Online Access:https://www.mdpi.com/2077-0383/12/4/1539

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