Survival Differences in Men and Women With Primary Malignant Cardiac Tumor: An Analysis Using the Surveillance, Epidemiology and End Results (SEER) Database From 1973 to 2015
Background No data are available on sex disparities in prevalence and survival for primary malignant cardiac tumors (PMCT). This study aimed to compare male and female PMCT prevalence and long‐term survival rates. Methods and Results We utilized the Surveillance, Epidemiology, and End Results (SEER)...
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| Format: | Article |
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Wiley
2020-05-01
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| Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| Subjects: | |
| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.119.014846 |
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| author | Daniel Antwi‐Amoabeng Zahara Meghji Samarthkumar Thakkar Mark B. Ulanja Mohamed Taha Devina Adalja Jaafar Al‐Khafaji Nageshwara Gullapalli Bryce D. Beutler Killian Boampong‐Konam Rajkumar Doshi |
| author_facet | Daniel Antwi‐Amoabeng Zahara Meghji Samarthkumar Thakkar Mark B. Ulanja Mohamed Taha Devina Adalja Jaafar Al‐Khafaji Nageshwara Gullapalli Bryce D. Beutler Killian Boampong‐Konam Rajkumar Doshi |
| author_sort | Daniel Antwi‐Amoabeng |
| collection | DOAJ |
| description | Background No data are available on sex disparities in prevalence and survival for primary malignant cardiac tumors (PMCT). This study aimed to compare male and female PMCT prevalence and long‐term survival rates. Methods and Results We utilized the Surveillance, Epidemiology, and End Results (SEER) 18 database from the National Cancer Institute for all PMCTs diagnosed between 1973 and 2015. From a total of 7 384 580 cases of cancer registered in SEER, we identified 327 men and 367 women with PMCTs. The majority (78%) of patients were white. Sarcoma was the most common type of PMCT in both men and women (≈60%). Individuals diagnosed with lymphoma exhibited better survival than those with other types of PMCTs. Men were diagnosed at a younger age than women; however, there was no significant difference in overall survival between the sexes. Men diagnosed with PMCT between the ages of 51 and 65 years demonstrated prolonged survival compared with those diagnosed at younger or older ages. There was no difference in survival rates among women based on age at diagnosis. Conclusions PMCTs are rare in both men and women. Tumors tend to be diagnosed at an earlier age in men compared with women, but there is no sex disparity in survival rate. Sarcoma is the most common type of PMCT, and lymphoma is associated with the highest survival rate among both sexes. |
| first_indexed | 2024-04-12T03:04:39Z |
| format | Article |
| id | doaj.art-0bfee820bac542d28640ae0884ef569a |
| institution | Directory Open Access Journal |
| issn | 2047-9980 |
| language | English |
| last_indexed | 2024-04-12T03:04:39Z |
| publishDate | 2020-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| spelling | doaj.art-0bfee820bac542d28640ae0884ef569a2022-12-22T03:50:32ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802020-05-0191010.1161/JAHA.119.014846Survival Differences in Men and Women With Primary Malignant Cardiac Tumor: An Analysis Using the Surveillance, Epidemiology and End Results (SEER) Database From 1973 to 2015Daniel Antwi‐Amoabeng0Zahara Meghji1Samarthkumar Thakkar2Mark B. Ulanja3Mohamed Taha4Devina Adalja5Jaafar Al‐Khafaji6Nageshwara Gullapalli7Bryce D. Beutler8Killian Boampong‐Konam9Rajkumar Doshi10Department of Internal Medicine University of Nevada Reno School of Medicine Reno NVDepartment of Internal Medicine University of Nevada Reno School of Medicine Reno NVDepartment of Internal Medicine Rochester General Hospital Rochester NYDepartment of Internal Medicine University of Nevada Reno School of Medicine Reno NVDepartment of Internal Medicine University of Nevada Reno School of Medicine Reno NVDepartment of General Medicine Gotri Medical Education and Research Center Vadodara Gujarat IndiaDepartment of Internal Medicine University of Nevada Reno School of Medicine Reno NVDepartment of Internal Medicine University of Nevada Reno School of Medicine Reno NVDepartment of Internal Medicine University of Nevada Reno School of Medicine Reno NVGhana Airport Clinc Limited Kotoka Internal Airport P.M.B KIA Accra GhanaDepartment of Internal Medicine University of Nevada Reno School of Medicine Reno NVBackground No data are available on sex disparities in prevalence and survival for primary malignant cardiac tumors (PMCT). This study aimed to compare male and female PMCT prevalence and long‐term survival rates. Methods and Results We utilized the Surveillance, Epidemiology, and End Results (SEER) 18 database from the National Cancer Institute for all PMCTs diagnosed between 1973 and 2015. From a total of 7 384 580 cases of cancer registered in SEER, we identified 327 men and 367 women with PMCTs. The majority (78%) of patients were white. Sarcoma was the most common type of PMCT in both men and women (≈60%). Individuals diagnosed with lymphoma exhibited better survival than those with other types of PMCTs. Men were diagnosed at a younger age than women; however, there was no significant difference in overall survival between the sexes. Men diagnosed with PMCT between the ages of 51 and 65 years demonstrated prolonged survival compared with those diagnosed at younger or older ages. There was no difference in survival rates among women based on age at diagnosis. Conclusions PMCTs are rare in both men and women. Tumors tend to be diagnosed at an earlier age in men compared with women, but there is no sex disparity in survival rate. Sarcoma is the most common type of PMCT, and lymphoma is associated with the highest survival rate among both sexes.https://www.ahajournals.org/doi/10.1161/JAHA.119.014846cardiac tumorsmalignancysexSurveillance, Epidemiology, and End Resultssurvival rate |
| spellingShingle | Daniel Antwi‐Amoabeng Zahara Meghji Samarthkumar Thakkar Mark B. Ulanja Mohamed Taha Devina Adalja Jaafar Al‐Khafaji Nageshwara Gullapalli Bryce D. Beutler Killian Boampong‐Konam Rajkumar Doshi Survival Differences in Men and Women With Primary Malignant Cardiac Tumor: An Analysis Using the Surveillance, Epidemiology and End Results (SEER) Database From 1973 to 2015 Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease cardiac tumors malignancy sex Surveillance, Epidemiology, and End Results survival rate |
| title | Survival Differences in Men and Women With Primary Malignant Cardiac Tumor: An Analysis Using the Surveillance, Epidemiology and End Results (SEER) Database From 1973 to 2015 |
| title_full | Survival Differences in Men and Women With Primary Malignant Cardiac Tumor: An Analysis Using the Surveillance, Epidemiology and End Results (SEER) Database From 1973 to 2015 |
| title_fullStr | Survival Differences in Men and Women With Primary Malignant Cardiac Tumor: An Analysis Using the Surveillance, Epidemiology and End Results (SEER) Database From 1973 to 2015 |
| title_full_unstemmed | Survival Differences in Men and Women With Primary Malignant Cardiac Tumor: An Analysis Using the Surveillance, Epidemiology and End Results (SEER) Database From 1973 to 2015 |
| title_short | Survival Differences in Men and Women With Primary Malignant Cardiac Tumor: An Analysis Using the Surveillance, Epidemiology and End Results (SEER) Database From 1973 to 2015 |
| title_sort | survival differences in men and women with primary malignant cardiac tumor an analysis using the surveillance epidemiology and end results seer database from 1973 to 2015 |
| topic | cardiac tumors malignancy sex Surveillance, Epidemiology, and End Results survival rate |
| url | https://www.ahajournals.org/doi/10.1161/JAHA.119.014846 |
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