The flavonoid corylin exhibits lifespan extension properties in mouse
Various traditional Chinese herbs and complex formulas have been suggested to exhibit lifespan extension properties. Here, the authors isolated the flavonoid corylin from Psoralea corylifolia and demonstrated its longevity properties in yeast, human cells and mouse.
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-28908-2 |
| _version_ | 1818137685610463232 |
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| author | Tong-Hong Wang Wei-Che Tseng Yann-Lii Leu Chi-Yuan Chen Wen-Chih Lee Ying-Chih Chi Shu-Fang Cheng Chun-Yu Lai Chen-Hsin Kuo Shu-Ling Yang Sien-Hung Yang Jiann-Jong Shen Chun-Hao Feng Chih-Ching Wu Tsong-Long Hwang Chia-Jen Wang Shu-Huei Wang Chin-Chuan Chen |
| author_facet | Tong-Hong Wang Wei-Che Tseng Yann-Lii Leu Chi-Yuan Chen Wen-Chih Lee Ying-Chih Chi Shu-Fang Cheng Chun-Yu Lai Chen-Hsin Kuo Shu-Ling Yang Sien-Hung Yang Jiann-Jong Shen Chun-Hao Feng Chih-Ching Wu Tsong-Long Hwang Chia-Jen Wang Shu-Huei Wang Chin-Chuan Chen |
| author_sort | Tong-Hong Wang |
| collection | DOAJ |
| description | Various traditional Chinese herbs and complex formulas have been suggested to exhibit lifespan extension properties. Here, the authors isolated the flavonoid corylin from Psoralea corylifolia and demonstrated its longevity properties in yeast, human cells and mouse. |
| first_indexed | 2024-12-11T10:00:14Z |
| format | Article |
| id | doaj.art-0c0473170acb4c4b99c95e471322f0fb |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-11T10:00:14Z |
| publishDate | 2022-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-0c0473170acb4c4b99c95e471322f0fb2022-12-22T01:12:08ZengNature PortfolioNature Communications2041-17232022-03-0113111610.1038/s41467-022-28908-2The flavonoid corylin exhibits lifespan extension properties in mouseTong-Hong Wang0Wei-Che Tseng1Yann-Lii Leu2Chi-Yuan Chen3Wen-Chih Lee4Ying-Chih Chi5Shu-Fang Cheng6Chun-Yu Lai7Chen-Hsin Kuo8Shu-Ling Yang9Sien-Hung Yang10Jiann-Jong Shen11Chun-Hao Feng12Chih-Ching Wu13Tsong-Long Hwang14Chia-Jen Wang15Shu-Huei Wang16Chin-Chuan Chen17Tissue Bank, Chang Gung Memorial HospitalGraduate Institute of Natural Products, Chang Gung UniversityTissue Bank, Chang Gung Memorial HospitalTissue Bank, Chang Gung Memorial HospitalOffice of Research and Development, Tzu Chi UniversityCryo-EM Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical CenterGraduate Institute of Natural Products, Chang Gung UniversityGraduate Institute of Natural Products, Chang Gung UniversityGraduate Institute of Natural Products, Chang Gung UniversitySchool of Traditional Chinese Medicine, Chang Gung UniversitySchool of Traditional Chinese Medicine, Chang Gung UniversitySchool of Traditional Chinese Medicine, Chang Gung UniversityGraduate Institute of Natural Products, Chang Gung UniversityDepartment of Medical Biotechnology and Laboratory Science, Chang Gung UniversityGraduate Institute of Health Industry Technology, Research Center for Food and Cosmetic Safety, Research Center for Chinese Herbal Medicine, College of Human Ecology, Chang Gung University of Science and TechnologyCell Therapy Core Laboratory, Chang Gung Memorial HospitalDepartment of Anatomy and Cell Biology, College of Medicine, National Taiwan UniversityTissue Bank, Chang Gung Memorial HospitalVarious traditional Chinese herbs and complex formulas have been suggested to exhibit lifespan extension properties. Here, the authors isolated the flavonoid corylin from Psoralea corylifolia and demonstrated its longevity properties in yeast, human cells and mouse.https://doi.org/10.1038/s41467-022-28908-2 |
| spellingShingle | Tong-Hong Wang Wei-Che Tseng Yann-Lii Leu Chi-Yuan Chen Wen-Chih Lee Ying-Chih Chi Shu-Fang Cheng Chun-Yu Lai Chen-Hsin Kuo Shu-Ling Yang Sien-Hung Yang Jiann-Jong Shen Chun-Hao Feng Chih-Ching Wu Tsong-Long Hwang Chia-Jen Wang Shu-Huei Wang Chin-Chuan Chen The flavonoid corylin exhibits lifespan extension properties in mouse Nature Communications |
| title | The flavonoid corylin exhibits lifespan extension properties in mouse |
| title_full | The flavonoid corylin exhibits lifespan extension properties in mouse |
| title_fullStr | The flavonoid corylin exhibits lifespan extension properties in mouse |
| title_full_unstemmed | The flavonoid corylin exhibits lifespan extension properties in mouse |
| title_short | The flavonoid corylin exhibits lifespan extension properties in mouse |
| title_sort | flavonoid corylin exhibits lifespan extension properties in mouse |
| url | https://doi.org/10.1038/s41467-022-28908-2 |
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