The Role of Tumour Metabolism in Cisplatin Resistance

The Role of Tumour Metabolism in Cisplatin Resistance

Cisplatin is a chemotherapy drug commonly used in cancer treatment. Tumour cells are more sensitive to cisplatin than normal cells. Cisplatin exerts an antitumour effect by interfering with DNA replication and transcription processes. However, the drug-resistance properties of tumour cells often cau...

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Bibliographic Details
Main Authors: Lude Wang, Xiaoya Zhao, Jianfei Fu, Wenxia Xu, Jianlie Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
tumour metabolism
cisplatin
resistance
DNA damage repair
ROS
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.691795/full

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