Evaluating apolipoprotein E genotype status and neuroprotective effects against white matter hyperintensity development in high-altitude careers

Evaluating apolipoprotein E genotype status and neuroprotective effects against white matter hyperintensity development in high-altitude careers

Abstract Objective This study considers the use of a rapid molecular assay to evaluate apolipoprotein E (ApoE) status in military subjects who have been exposed to high altitude. We hypothesize that ApoE status may be protective against developing brain white matter hyperintensities (WMHs) after hig...

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Bibliographic Details
Main Authors: Richard R. Chapleau, CharLee A. Martin, Summer R. Hughes, James C. Baldwin, John Sladky, Paul M. Sherman, Michael Grinkemeyer
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Research Notes
Subjects:
Apolipoprotein E
High altitude acclimatization
Neuroprotection
Genotype screening
Online Access:http://link.springer.com/article/10.1186/s13104-018-3867-7

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