Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock room
Life-threatening bleeding in anticoagulation with Warfarin is an emergency challenging issue. Several approaches are available to treat bleeding in either over-anticoagulation or propeanticoagulation, including vitamin K, fresh frozen plasma and prothrombin complex concentrates (PCC) administration....
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Format: | Article |
Language: | English |
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MDPI AG
2015-03-01
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Series: | Hematology Reports |
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Online Access: | http://www.pagepress.org/journals/index.php/hr/article/view/5656 |
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author | Alessandro Morotti Mauro Felice Frascisco |
author_facet | Alessandro Morotti Mauro Felice Frascisco |
author_sort | Alessandro Morotti |
collection | DOAJ |
description | Life-threatening bleeding in anticoagulation with Warfarin is an emergency challenging issue. Several approaches are available to treat bleeding in either over-anticoagulation or propeanticoagulation, including vitamin K, fresh frozen plasma and prothrombin complex concentrates (PCC) administration. In coexisting trauma-induced bleeding and anticoagulation, reversal of anticoagulation must be a rapid and highly effective procedure. Furthermore the appropriate treatment must be directly available in each shock rooms to guarantee the rapid management of the emergency. PCC require a simple storage, rapid accessibility, fast administration procedures and high effectiveness. Here we report the utility of PCC in management of a craniofacial trauma in proper-anticoagulation. |
first_indexed | 2024-04-10T18:35:57Z |
format | Article |
id | doaj.art-0c0eafb171294dc19c7b894826fcb683 |
institution | Directory Open Access Journal |
issn | 2038-8322 2038-8330 |
language | English |
last_indexed | 2024-04-10T18:35:57Z |
publishDate | 2015-03-01 |
publisher | MDPI AG |
record_format | Article |
series | Hematology Reports |
spelling | doaj.art-0c0eafb171294dc19c7b894826fcb6832023-02-02T01:22:11ZengMDPI AGHematology Reports2038-83222038-83302015-03-017110.4081/hr.2015.56563026Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock roomAlessandro Morotti0Mauro Felice Frascisco1Department of Internal Medicine, San Luigi Hospital, University of TurinDepartment of Internal Medicine, San Luigi Hospital, University of TurinLife-threatening bleeding in anticoagulation with Warfarin is an emergency challenging issue. Several approaches are available to treat bleeding in either over-anticoagulation or propeanticoagulation, including vitamin K, fresh frozen plasma and prothrombin complex concentrates (PCC) administration. In coexisting trauma-induced bleeding and anticoagulation, reversal of anticoagulation must be a rapid and highly effective procedure. Furthermore the appropriate treatment must be directly available in each shock rooms to guarantee the rapid management of the emergency. PCC require a simple storage, rapid accessibility, fast administration procedures and high effectiveness. Here we report the utility of PCC in management of a craniofacial trauma in proper-anticoagulation.http://www.pagepress.org/journals/index.php/hr/article/view/5656life-threatening bleeding, anticoagulation, prothrombin complex concentrates |
spellingShingle | Alessandro Morotti Mauro Felice Frascisco Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock room Hematology Reports life-threatening bleeding, anticoagulation, prothrombin complex concentrates |
title | Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock room |
title_full | Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock room |
title_fullStr | Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock room |
title_full_unstemmed | Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock room |
title_short | Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock room |
title_sort | emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation utility of prothrombin complex concentrates in the shock room |
topic | life-threatening bleeding, anticoagulation, prothrombin complex concentrates |
url | http://www.pagepress.org/journals/index.php/hr/article/view/5656 |
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