Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock room

Life-threatening bleeding in anticoagulation with Warfarin is an emergency challenging issue. Several approaches are available to treat bleeding in either over-anticoagulation or propeanticoagulation, including vitamin K, fresh frozen plasma and prothrombin complex concentrates (PCC) administration....

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Main Authors: Alessandro Morotti, Mauro Felice Frascisco
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Hematology Reports
Subjects:
Online Access:http://www.pagepress.org/journals/index.php/hr/article/view/5656
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author Alessandro Morotti
Mauro Felice Frascisco
author_facet Alessandro Morotti
Mauro Felice Frascisco
author_sort Alessandro Morotti
collection DOAJ
description Life-threatening bleeding in anticoagulation with Warfarin is an emergency challenging issue. Several approaches are available to treat bleeding in either over-anticoagulation or propeanticoagulation, including vitamin K, fresh frozen plasma and prothrombin complex concentrates (PCC) administration. In coexisting trauma-induced bleeding and anticoagulation, reversal of anticoagulation must be a rapid and highly effective procedure. Furthermore the appropriate treatment must be directly available in each shock rooms to guarantee the rapid management of the emergency. PCC require a simple storage, rapid accessibility, fast administration procedures and high effectiveness. Here we report the utility of PCC in management of a craniofacial trauma in proper-anticoagulation.
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spelling doaj.art-0c0eafb171294dc19c7b894826fcb6832023-02-02T01:22:11ZengMDPI AGHematology Reports2038-83222038-83302015-03-017110.4081/hr.2015.56563026Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock roomAlessandro Morotti0Mauro Felice Frascisco1Department of Internal Medicine, San Luigi Hospital, University of TurinDepartment of Internal Medicine, San Luigi Hospital, University of TurinLife-threatening bleeding in anticoagulation with Warfarin is an emergency challenging issue. Several approaches are available to treat bleeding in either over-anticoagulation or propeanticoagulation, including vitamin K, fresh frozen plasma and prothrombin complex concentrates (PCC) administration. In coexisting trauma-induced bleeding and anticoagulation, reversal of anticoagulation must be a rapid and highly effective procedure. Furthermore the appropriate treatment must be directly available in each shock rooms to guarantee the rapid management of the emergency. PCC require a simple storage, rapid accessibility, fast administration procedures and high effectiveness. Here we report the utility of PCC in management of a craniofacial trauma in proper-anticoagulation.http://www.pagepress.org/journals/index.php/hr/article/view/5656life-threatening bleeding, anticoagulation, prothrombin complex concentrates
spellingShingle Alessandro Morotti
Mauro Felice Frascisco
Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock room
Hematology Reports
life-threatening bleeding, anticoagulation, prothrombin complex concentrates
title Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock room
title_full Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock room
title_fullStr Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock room
title_full_unstemmed Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock room
title_short Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock room
title_sort emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation utility of prothrombin complex concentrates in the shock room
topic life-threatening bleeding, anticoagulation, prothrombin complex concentrates
url http://www.pagepress.org/journals/index.php/hr/article/view/5656
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