RIPK3 and caspase 8 collaborate to limit herpes simplex encephalitis.
Invasion of the brain by herpes simplex virus 1 (HSV1) can lead to the development of herpes simplex encephalitis (HSE) that is often associated with significant morbidity and mortality regardless of therapeutic intervention. Both virus and host immune factors dictate HSE onset and progression. Beca...
Main Authors: | Hongyan Guo, Heather S Koehler, Edward S Mocarski, Richard D Dix |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-09-01
|
Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1010857 |
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