Oca2 targeting using CRISPR/Cas9 in the Malawi cichlid Astatotilapia calliptera

Oca2 targeting using CRISPR/Cas9 in the Malawi cichlid Astatotilapia calliptera

Identifying genetic loci underlying trait variation provides insights into the mechanisms of diversification, but demonstrating causality and characterizing the role of genetic loci requires testing candidate gene function, often in non-model species. Here we establish CRISPR/Cas9 editing in Astatot...

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Bibliographic Details
Main Authors: Bethan Clark, Joel Elkin, Aleksandra Marconi, George F. Turner, Alan M. Smith, Domino Joyce, Eric A. Miska, Scott A. Juntti, M. Emília Santos
Format: Article
Language:English
Published: The Royal Society 2022-04-01
Series:Royal Society Open Science
Subjects:
cichlids
CRISPR/Cas9
adaptive radiation
functional genetics
evo-devo
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.220077

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