Medullary Solitary Plasmacytoma of Maxilla- A Rare Case Report
Solitary Plasmacytoma (SP) is a rare disease characterised by a localised proliferation of neoplastic monoclonal plasma cells, without evidence of systemic disease. The aetiology of SP remains unknown, but chronic stimulation, overdose irradiation, viruses, and gene interactions in the reticuloend...
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| Format: | Article |
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JCDR Research and Publications Private Limited
2022-10-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/17045/58839_CE(OM)_F[SH]_PF1(AKA_OM)_PFA(SS)_PN(SS).pdf |
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| author | Jigna S Shah Jaya Dubey |
| author_facet | Jigna S Shah Jaya Dubey |
| author_sort | Jigna S Shah |
| collection | DOAJ |
| description | Solitary Plasmacytoma (SP) is a rare disease characterised by a localised proliferation of neoplastic monoclonal plasma cells, without
evidence of systemic disease. The aetiology of SP remains unknown, but chronic stimulation, overdose irradiation, viruses, and gene
interactions in the reticuloendothelial system have been suggested as the aetiologic factor. While pain is the most common symptom of
osseous mandible SP, it is usually painless in the maxilla and may manifest orally with paresthesia, swelling, soft tissue masses, mobility
and migration of teeth, haemorrhage, or pathologic fracture due to cortical destruction of bone. Because the amount of haemopoitic bone
marrow in the maxilla is decreased, oral involvement of the maxilla is less common than that of the mandible. Here, authors reported a case
of 46-year-old male patient presented with the chief complaint of mobility of his upper left back teeth and swelling over his left-side palatal
area. Clinical examination was suggestive of benign odontogenic tumors and salivary gland tumors, while two-Dimensional (2D) and
three-Dimensional (3D) imaging were suggestive of malignant tumors arising from either alveolar bone or maxillary sinus. The laboratory
investigations and biopsy revealed solitary plasmacytoma of maxilla. There were clinical symptoms of paresthesia and mobility, but no
other signs of malignancy were observed. As the case report concludes, all necessary investigations need to be conducted to exclude all
other pathologies, so that treatment can begin as soon as possible. |
| first_indexed | 2024-04-10T21:36:39Z |
| format | Article |
| id | doaj.art-0c117cdd8fe74e9ea1bc26fec0f89886 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-04-10T21:36:39Z |
| publishDate | 2022-10-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-0c117cdd8fe74e9ea1bc26fec0f898862023-01-19T10:51:26ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2022-10-011610 ZD15ZD1710.7860/JCDR/2022/58839.17045Medullary Solitary Plasmacytoma of Maxilla- A Rare Case ReportJigna S Shah0Jaya Dubey1Professor and Head, Department of Oral Medicine and Radiology, Government Dental College and Hospital, Ahmedabad, Gujarat, India.Postgraduate Student, Department of Oral Medicine and Radiology, Government Dental College and Hospital, Ahmedabad, Gujarat, India.Solitary Plasmacytoma (SP) is a rare disease characterised by a localised proliferation of neoplastic monoclonal plasma cells, without evidence of systemic disease. The aetiology of SP remains unknown, but chronic stimulation, overdose irradiation, viruses, and gene interactions in the reticuloendothelial system have been suggested as the aetiologic factor. While pain is the most common symptom of osseous mandible SP, it is usually painless in the maxilla and may manifest orally with paresthesia, swelling, soft tissue masses, mobility and migration of teeth, haemorrhage, or pathologic fracture due to cortical destruction of bone. Because the amount of haemopoitic bone marrow in the maxilla is decreased, oral involvement of the maxilla is less common than that of the mandible. Here, authors reported a case of 46-year-old male patient presented with the chief complaint of mobility of his upper left back teeth and swelling over his left-side palatal area. Clinical examination was suggestive of benign odontogenic tumors and salivary gland tumors, while two-Dimensional (2D) and three-Dimensional (3D) imaging were suggestive of malignant tumors arising from either alveolar bone or maxillary sinus. The laboratory investigations and biopsy revealed solitary plasmacytoma of maxilla. There were clinical symptoms of paresthesia and mobility, but no other signs of malignancy were observed. As the case report concludes, all necessary investigations need to be conducted to exclude all other pathologies, so that treatment can begin as soon as possible.https://www.jcdr.net/articles/PDF/17045/58839_CE(OM)_F[SH]_PF1(AKA_OM)_PFA(SS)_PN(SS).pdfextramedullary plasmacytomashard palatemultiple myelomaswelling |
| spellingShingle | Jigna S Shah Jaya Dubey Medullary Solitary Plasmacytoma of Maxilla- A Rare Case Report Journal of Clinical and Diagnostic Research extramedullary plasmacytomas hard palate multiple myeloma swelling |
| title | Medullary Solitary Plasmacytoma of Maxilla- A Rare Case Report |
| title_full | Medullary Solitary Plasmacytoma of Maxilla- A Rare Case Report |
| title_fullStr | Medullary Solitary Plasmacytoma of Maxilla- A Rare Case Report |
| title_full_unstemmed | Medullary Solitary Plasmacytoma of Maxilla- A Rare Case Report |
| title_short | Medullary Solitary Plasmacytoma of Maxilla- A Rare Case Report |
| title_sort | medullary solitary plasmacytoma of maxilla a rare case report |
| topic | extramedullary plasmacytomas hard palate multiple myeloma swelling |
| url | https://www.jcdr.net/articles/PDF/17045/58839_CE(OM)_F[SH]_PF1(AKA_OM)_PFA(SS)_PN(SS).pdf |
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