Epidemiology and treatment of beta thalassemia major in China
Abstract Thalassemia, classified as the main types α‐ and β‐thalassemia, is a single gene disorder resulting from globin chain synthesis impairment through the mutation or deletion of globin genes. The incidence of thalassemia is high worldwide, with high associated mortality. Therefore, treatment i...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-03-01
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| Series: | Pediatric Investigation |
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| Online Access: | https://doi.org/10.1002/ped4.12154 |
| _version_ | 1818948132282564608 |
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| author | Xiaoxiao Xu Xuedong Wu |
| author_facet | Xiaoxiao Xu Xuedong Wu |
| author_sort | Xiaoxiao Xu |
| collection | DOAJ |
| description | Abstract Thalassemia, classified as the main types α‐ and β‐thalassemia, is a single gene disorder resulting from globin chain synthesis impairment through the mutation or deletion of globin genes. The incidence of thalassemia is high worldwide, with high associated mortality. Therefore, treatment is important to improve patient outcomes. This paper reviews the current status of β‐thalassemia major in China, including its epidemiology and treatment. |
| first_indexed | 2024-12-20T08:41:56Z |
| format | Article |
| id | doaj.art-0c14f5e980ce43a28089375b042af747 |
| institution | Directory Open Access Journal |
| issn | 2574-2272 |
| language | English |
| last_indexed | 2024-12-20T08:41:56Z |
| publishDate | 2020-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pediatric Investigation |
| spelling | doaj.art-0c14f5e980ce43a28089375b042af7472022-12-21T19:46:22ZengWileyPediatric Investigation2574-22722020-03-0141434710.1002/ped4.12154Epidemiology and treatment of beta thalassemia major in ChinaXiaoxiao Xu0Xuedong Wu1Departments of pediatrics Nanfang Hospital Southern Medical University Guangzhou Guangdong ChinaDepartments of pediatrics Nanfang Hospital Southern Medical University Guangzhou Guangdong ChinaAbstract Thalassemia, classified as the main types α‐ and β‐thalassemia, is a single gene disorder resulting from globin chain synthesis impairment through the mutation or deletion of globin genes. The incidence of thalassemia is high worldwide, with high associated mortality. Therefore, treatment is important to improve patient outcomes. This paper reviews the current status of β‐thalassemia major in China, including its epidemiology and treatment.https://doi.org/10.1002/ped4.12154ThalassemiaEpidemiologyTreatmentChina |
| spellingShingle | Xiaoxiao Xu Xuedong Wu Epidemiology and treatment of beta thalassemia major in China Pediatric Investigation Thalassemia Epidemiology Treatment China |
| title | Epidemiology and treatment of beta thalassemia major in China |
| title_full | Epidemiology and treatment of beta thalassemia major in China |
| title_fullStr | Epidemiology and treatment of beta thalassemia major in China |
| title_full_unstemmed | Epidemiology and treatment of beta thalassemia major in China |
| title_short | Epidemiology and treatment of beta thalassemia major in China |
| title_sort | epidemiology and treatment of beta thalassemia major in china |
| topic | Thalassemia Epidemiology Treatment China |
| url | https://doi.org/10.1002/ped4.12154 |
| work_keys_str_mv | AT xiaoxiaoxu epidemiologyandtreatmentofbetathalassemiamajorinchina AT xuedongwu epidemiologyandtreatmentofbetathalassemiamajorinchina |