Mitigating effects and mechanisms of Tai Chi on mild cognitive impairment in the elderly
Mild cognitive impairment (MCI) is a major public health concern that endangers health and decreases the quality of life of the elderly around the world. A recent clinical guideline has recommended regular exercise (twice per week) for patients with MCI as part of an overall approach to management....
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Aging Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2022.1028822/full |
| _version_ | 1797943418994819072 |
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| author | Xin Wang Keyi Si Wei Gu Xueqiang Wang Xueqiang Wang |
| author_facet | Xin Wang Keyi Si Wei Gu Xueqiang Wang Xueqiang Wang |
| author_sort | Xin Wang |
| collection | DOAJ |
| description | Mild cognitive impairment (MCI) is a major public health concern that endangers health and decreases the quality of life of the elderly around the world. A recent clinical guideline has recommended regular exercise (twice per week) for patients with MCI as part of an overall approach to management. Tai Chi, a form of light-to-moderate-intensity mind-body exercise, is particularly suitable for seniors. This review aims to summarize epidemiological studies related to the effects of Tai Chi on symptom remission in older adults with MCI and reveal the potential mechanisms. Evidence suggested that Tai Chi can improve cognitive functions and alleviate the accompanying symptoms of MCI in the elderly potentially by activating the expression of signals in different brain regions, altering their connectivity, increasing the brain volume, and modulating brain-derived neurotropic and inflammation factors. Studies comparing various types of Tai Chi may contribute to the identification of paradigms that have appropriate intensities and difficulty and exert good effects on older people with MCI. In addition, studies are warranted to determine the frequency and duration of training that can optimize the beneficial effects of Tai Chi on MCI. |
| first_indexed | 2024-04-10T20:22:46Z |
| format | Article |
| id | doaj.art-0c1950829a874c25b7e657a8c5817434 |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-04-10T20:22:46Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-0c1950829a874c25b7e657a8c58174342023-01-25T13:32:02ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652023-01-011410.3389/fnagi.2022.10288221028822Mitigating effects and mechanisms of Tai Chi on mild cognitive impairment in the elderlyXin Wang0Keyi Si1Wei Gu2Xueqiang Wang3Xueqiang Wang4Faculty of Traditional Chinese Medicine, Naval Medical University, Shanghai, ChinaDepartment of Military Health Statistics, Naval Medical University, Shanghai, ChinaFaculty of Traditional Chinese Medicine, Naval Medical University, Shanghai, ChinaDepartment of Sport Rehabilitation, Shanghai University of Sport, Shanghai, ChinaDepartment of Rehabilitation Medicine, Shanghai Shangti Orthopaedic Hospital, Shanghai, ChinaMild cognitive impairment (MCI) is a major public health concern that endangers health and decreases the quality of life of the elderly around the world. A recent clinical guideline has recommended regular exercise (twice per week) for patients with MCI as part of an overall approach to management. Tai Chi, a form of light-to-moderate-intensity mind-body exercise, is particularly suitable for seniors. This review aims to summarize epidemiological studies related to the effects of Tai Chi on symptom remission in older adults with MCI and reveal the potential mechanisms. Evidence suggested that Tai Chi can improve cognitive functions and alleviate the accompanying symptoms of MCI in the elderly potentially by activating the expression of signals in different brain regions, altering their connectivity, increasing the brain volume, and modulating brain-derived neurotropic and inflammation factors. Studies comparing various types of Tai Chi may contribute to the identification of paradigms that have appropriate intensities and difficulty and exert good effects on older people with MCI. In addition, studies are warranted to determine the frequency and duration of training that can optimize the beneficial effects of Tai Chi on MCI.https://www.frontiersin.org/articles/10.3389/fnagi.2022.1028822/fullTai Chimild cognitive impairmentelderlycognitive functionmechanism |
| spellingShingle | Xin Wang Keyi Si Wei Gu Xueqiang Wang Xueqiang Wang Mitigating effects and mechanisms of Tai Chi on mild cognitive impairment in the elderly Frontiers in Aging Neuroscience Tai Chi mild cognitive impairment elderly cognitive function mechanism |
| title | Mitigating effects and mechanisms of Tai Chi on mild cognitive impairment in the elderly |
| title_full | Mitigating effects and mechanisms of Tai Chi on mild cognitive impairment in the elderly |
| title_fullStr | Mitigating effects and mechanisms of Tai Chi on mild cognitive impairment in the elderly |
| title_full_unstemmed | Mitigating effects and mechanisms of Tai Chi on mild cognitive impairment in the elderly |
| title_short | Mitigating effects and mechanisms of Tai Chi on mild cognitive impairment in the elderly |
| title_sort | mitigating effects and mechanisms of tai chi on mild cognitive impairment in the elderly |
| topic | Tai Chi mild cognitive impairment elderly cognitive function mechanism |
| url | https://www.frontiersin.org/articles/10.3389/fnagi.2022.1028822/full |
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