COVID-19 and the Pancreas: A Narrative Review
The outbreak of COVID-19, initially developed in China in early December 2019, has rapidly spread to other countries and represents a public health emergency of international concern. COVID-19 has caused great concern about respiratory symptoms, but it is worth noting that it can also affect the gas...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-08-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/12/9/1292 |
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| author | Emanuele Sinagra Endrit Shahini Federica Crispino Ina Macaione Valentina Guarnotta Marta Marasà Sergio Testai Socrate Pallio Domenico Albano Antonio Facciorusso Marcello Maida |
| author_facet | Emanuele Sinagra Endrit Shahini Federica Crispino Ina Macaione Valentina Guarnotta Marta Marasà Sergio Testai Socrate Pallio Domenico Albano Antonio Facciorusso Marcello Maida |
| author_sort | Emanuele Sinagra |
| collection | DOAJ |
| description | The outbreak of COVID-19, initially developed in China in early December 2019, has rapidly spread to other countries and represents a public health emergency of international concern. COVID-19 has caused great concern about respiratory symptoms, but it is worth noting that it can also affect the gastrointestinal tract. However, the data on pancreatic involvement during SARS-CoV-2 infection are limited. The prevalence and severity of pancreatic damage and acute pancreatitis, as well as its pathophysiology, are still under debate. Moreover, the possible implication of pancreatic damage as an apparent adverse effect of COVID-19 therapies or vaccines are issues that need to be addressed. Finally, the COVID-19 pandemic has generated delays and organizational consequences for pancreatic surgery, an element that represent indirect damage from COVID-19. This narrative review aims to summarize and analyze all the aspects of pancreatic involvement in COVID-19 patients, trying to establish the possible underlying mechanisms and scientific evidence supporting the association between COVID-19 and pancreatic disease. |
| first_indexed | 2024-03-09T23:24:00Z |
| format | Article |
| id | doaj.art-0c19ad47ad0f41018bde1dc9b6db9b65 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-09T23:24:00Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-0c19ad47ad0f41018bde1dc9b6db9b652023-11-23T17:21:39ZengMDPI AGLife2075-17292022-08-01129129210.3390/life12091292COVID-19 and the Pancreas: A Narrative ReviewEmanuele Sinagra0Endrit Shahini1Federica Crispino2Ina Macaione3Valentina Guarnotta4Marta Marasà5Sergio Testai6Socrate Pallio7Domenico Albano8Antonio Facciorusso9Marcello Maida10Gastroenterology and Endoscopy Unit, Fondazione Istituto G. Giglio, Contrada Pietra Pollastra Pisciotto, 90015 Cefalù, ItalyDivision of Gastroenterology, National Institute of Research “Saverio De Bellis”, Via Turi, 27, Castellana Grotte, 70013 Bari, ItalyDepartment of Health Promotion Sciences Maternal and Infant Care, Section of Gastroenterology & Hepatology, Internal Medicine and Medical Specialties, PROMISE, University of Palermo, 90133 Palermo, ItalySurgery Unit, Fondazione Istituto G. Giglio, Contrada Pietra Pollastra Pisciotto, 90015 Cefalù, ItalySection of Endocrinology, Department of Health Promotion Sciences, Maternal-Infant Care, Internal Medicine and Specialties of Excellence “G.D’Alessandro” (PROMISE), University Hospital P. Giaccone, University of Palermo, Piazza Delle Cliniche 2, 90133 Palermo, ItalyRadiology Unit, Fondazione Istituto G. Giglio, Contrada Pietra Pollastra Pisciotto, 90015 Cefalù, ItalyRadiology Unit, Fondazione Istituto G. Giglio, Contrada Pietra Pollastra Pisciotto, 90015 Cefalù, ItalyEndoscopy Unit, Department of Clinical and Experimental Medicine, University of Messina, AOUP Policlinico G. Martino, 98122 Messina, ItalyIRCCS Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161 Milan, ItalyGastroenterology Unit, Department of Medical Sciences, University of Foggia, 71122 Foggia, ItalyGastroenterology and Endoscopy Unit, S. Elia-Raimondi Hospital, 93100 Caltanissetta, ItalyThe outbreak of COVID-19, initially developed in China in early December 2019, has rapidly spread to other countries and represents a public health emergency of international concern. COVID-19 has caused great concern about respiratory symptoms, but it is worth noting that it can also affect the gastrointestinal tract. However, the data on pancreatic involvement during SARS-CoV-2 infection are limited. The prevalence and severity of pancreatic damage and acute pancreatitis, as well as its pathophysiology, are still under debate. Moreover, the possible implication of pancreatic damage as an apparent adverse effect of COVID-19 therapies or vaccines are issues that need to be addressed. Finally, the COVID-19 pandemic has generated delays and organizational consequences for pancreatic surgery, an element that represent indirect damage from COVID-19. This narrative review aims to summarize and analyze all the aspects of pancreatic involvement in COVID-19 patients, trying to establish the possible underlying mechanisms and scientific evidence supporting the association between COVID-19 and pancreatic disease.https://www.mdpi.com/2075-1729/12/9/1292COVID-19SARS-CoV-2coronaviruspancreaspancreatitis |
| spellingShingle | Emanuele Sinagra Endrit Shahini Federica Crispino Ina Macaione Valentina Guarnotta Marta Marasà Sergio Testai Socrate Pallio Domenico Albano Antonio Facciorusso Marcello Maida COVID-19 and the Pancreas: A Narrative Review Life COVID-19 SARS-CoV-2 coronavirus pancreas pancreatitis |
| title | COVID-19 and the Pancreas: A Narrative Review |
| title_full | COVID-19 and the Pancreas: A Narrative Review |
| title_fullStr | COVID-19 and the Pancreas: A Narrative Review |
| title_full_unstemmed | COVID-19 and the Pancreas: A Narrative Review |
| title_short | COVID-19 and the Pancreas: A Narrative Review |
| title_sort | covid 19 and the pancreas a narrative review |
| topic | COVID-19 SARS-CoV-2 coronavirus pancreas pancreatitis |
| url | https://www.mdpi.com/2075-1729/12/9/1292 |
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