Mir-675-5p supports hypoxia-induced drug resistance in colorectal cancer cells

Mir-675-5p supports hypoxia-induced drug resistance in colorectal cancer cells

Abstract Background The uncontrolled proliferation of cancer cells determines hypoxic conditions within the neoplastic mass with consequent activation of specific molecular pathways that allow cells to survive despite oxygen deprivation. The same molecular pathways are often the cause of chemoresist...

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Bibliographic Details
Main Authors: Chiara Zichittella, Maria Magdalena Barreca, Aurora Cordaro, Chiara Corrado, Riccardo Alessandro, Alice Conigliaro
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Cancer
Subjects:
Colorectal cancer (CRC)
Hypoxia
MicroRNA
Drug resistance
Apoptosis
5-fluorouracil (5-FU)
Online Access:https://doi.org/10.1186/s12885-022-09666-2

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