Contemporary Circulating Enterovirus D68 Strains Have Acquired the Capacity for Viral Entry and Replication in Human Neuronal Cells

Contemporary Circulating Enterovirus D68 Strains Have Acquired the Capacity for Viral Entry and Replication in Human Neuronal Cells

ABSTRACT Enterovirus D68 (EV-D68) has historically been associated with respiratory illnesses. However, in the summers of 2014 and 2016, EV-D68 outbreaks coincided with a spike in polio-like acute flaccid myelitis/paralysis (AFM/AFP) cases. This raised concerns that EV-D68 could be the causative age...

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Bibliographic Details
Main Authors: David M. Brown, Alison M. Hixon, Lauren M. Oldfield, Yun Zhang, Mark Novotny, Wei Wang, Suman R. Das, Reed S. Shabman, Kenneth L. Tyler, Richard H. Scheuermann
Format: Article
Language:English
Published: American Society for Microbiology 2018-11-01
Series:mBio
Subjects:
EV-D68
SH-SY5Y
enterovirus
myelitis
neurotropism
neurovirology
Online Access:https://journals.asm.org/doi/10.1128/mBio.01954-18

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