Thoracic low grade glial neoplasm with concurrent H3 K27M and PTPN11 mutations

Thoracic low grade glial neoplasm with concurrent H3 K27M and PTPN11 mutations

Abstract We present the case of a 41-year-old man who developed worsening mid-thoracic back pain and imaging revealed a well-circumscribed intramedullary tumor in the thoracic spinal cord. Subtotal resection was performed, and histopathological analysis showed a cytologically bland, minimally prolif...

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Bibliographic Details
Main Authors: Michael G. Argenziano, Julia L. Furnari, Michael L. Miller, Yu Sun, Matei A. Banu, Justin A. Neira, Matija Snuderl, Jeffrey N. Bruce, Mary Welch, Paul McCormick, Peter Canoll
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Acta Neuropathologica Communications
Subjects:
H3 K27M
Intramedullary tumor
Low grade glioma
PTPN11
MAPK signaling pathway
Online Access:https://doi.org/10.1186/s40478-022-01340-9

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