Mitochondria in Pathological Cardiac Hypertrophy Research and Therapy

Mitochondria in Pathological Cardiac Hypertrophy Research and Therapy

Cardiac hypertrophy, a stereotypic cardiac response to increased workload, ultimately progresses to severe contractile dysfunction and uncompensated heart failure without appropriate intervention. Sustained cardiac overload inevitably results in high energy consumption, thus breaking the balance bet...

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Bibliographic Details
Main Authors: Dan Yang, Han-Qing Liu, Fang-Yuan Liu, Zhen Guo, Peng An, Ming-Yu Wang, Zheng Yang, Di Fan, Qi-Zhu Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
mitochondria
cardiac hypertrophy
regulatory mechanisms
therapeutic strategies
mitophagy
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.822969/full

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