Formulation Options for Mucoadhesive Dosage Forms for Use in the Oral Cavity

Mucoadhesive dosage forms, which are used for topical application in the oral cavity, are currently a very intensively developing field in pharmaceutical technology. Considering the physiological conditions of the oral cavity, the formulation of these mucoadhesive forms is still a challenge. Various...

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Main Authors: Šimunková V., Tichý E., Špaglová M., Potúčková M.
Format: Article
Language:English
Published: Sciendo 2023-09-01
Series:European Pharmaceutical Journal
Subjects:
Online Access:https://doi.org/10.2478/afpuc-2023-0012
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author Šimunková V.
Tichý E.
Špaglová M.
Potúčková M.
author_facet Šimunková V.
Tichý E.
Špaglová M.
Potúčková M.
author_sort Šimunková V.
collection DOAJ
description Mucoadhesive dosage forms, which are used for topical application in the oral cavity, are currently a very intensively developing field in pharmaceutical technology. Considering the physiological conditions of the oral cavity, the formulation of these mucoadhesive forms is still a challenge. Various types and forms of polymers are used in the experiments, in combination with a large number of drugs, while the achieved effect can be local or systemic and the release rate can be controlled. For many drugs, buccal application is one of the ways to increase their bioavailability.
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spelling doaj.art-0c29470026b740d5bef85a95e51e1a9a2024-02-19T09:03:14ZengSciendoEuropean Pharmaceutical Journal2453-67252023-09-0170s1445110.2478/afpuc-2023-0012Formulation Options for Mucoadhesive Dosage Forms for Use in the Oral CavityŠimunková V.0Tichý E.1Špaglová M.2Potúčková M.3Comenius University Bratislava, Faculty of Pharmacy, Department of Galenic Pharmacy, Odbojárov 10, SK-832 32Bratislava, SlovakiaHameln rds s.r.o., Horná 36, SK-900 01Modra, SlovakiaComenius University Bratislava, Faculty of Pharmacy, Department of Galenic Pharmacy, Odbojárov 10, SK-832 32Bratislava, SlovakiaComenius University Bratislava, Faculty of Pharmacy, Department of Galenic Pharmacy, Odbojárov 10, SK-832 32Bratislava, SlovakiaMucoadhesive dosage forms, which are used for topical application in the oral cavity, are currently a very intensively developing field in pharmaceutical technology. Considering the physiological conditions of the oral cavity, the formulation of these mucoadhesive forms is still a challenge. Various types and forms of polymers are used in the experiments, in combination with a large number of drugs, while the achieved effect can be local or systemic and the release rate can be controlled. For many drugs, buccal application is one of the ways to increase their bioavailability.https://doi.org/10.2478/afpuc-2023-0012mucoadhesionpolymersbuccal applicationbuccal filmsmucoadhesive dosage forms
spellingShingle Šimunková V.
Tichý E.
Špaglová M.
Potúčková M.
Formulation Options for Mucoadhesive Dosage Forms for Use in the Oral Cavity
European Pharmaceutical Journal
mucoadhesion
polymers
buccal application
buccal films
mucoadhesive dosage forms
title Formulation Options for Mucoadhesive Dosage Forms for Use in the Oral Cavity
title_full Formulation Options for Mucoadhesive Dosage Forms for Use in the Oral Cavity
title_fullStr Formulation Options for Mucoadhesive Dosage Forms for Use in the Oral Cavity
title_full_unstemmed Formulation Options for Mucoadhesive Dosage Forms for Use in the Oral Cavity
title_short Formulation Options for Mucoadhesive Dosage Forms for Use in the Oral Cavity
title_sort formulation options for mucoadhesive dosage forms for use in the oral cavity
topic mucoadhesion
polymers
buccal application
buccal films
mucoadhesive dosage forms
url https://doi.org/10.2478/afpuc-2023-0012
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