ARTERIAL STIFFNESS PARAMETERS IN PATIENTS WITH MODERATE/HIGH CARDIOVASCULAR RISK DURING LISINOPRIL AND SIMVASTATIN TREATMENT
<p><strong>Aim.</strong> To evaluate parameters of arterial stiffness by non-invasive arteriography in patients with moderate/high cardiovascular risk receiving lisinopril and simvastatin.</p><p><strong>Material and methods.</strong> 20 patients (aged 50-55...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Столичная издательская компания
2016-01-01
|
| Series: | Рациональная фармакотерапия в кардиологии |
| Subjects: | |
| Online Access: | http://www.rpcardio.ru/jour/article/view/656 |
| _version_ | 1797727247455485952 |
|---|---|
| author | V. N. Isakova O. G. Garbuzova E. V. Klinkova E. V. Bandurko |
| author_facet | V. N. Isakova O. G. Garbuzova E. V. Klinkova E. V. Bandurko |
| author_sort | V. N. Isakova |
| collection | DOAJ |
| description | <p><strong>Aim.</strong> To evaluate parameters of arterial stiffness by non-invasive arteriography in patients with moderate/high cardiovascular risk receiving lisinopril and simvastatin.</p><p><strong>Material and methods.</strong> 20 patients (aged 50-55 y.o.) with arterial hypertension of the 1st degree and dislipidemia are included in the study. All patients had pulse wave velocity (PWV) ≥ 10 m/s and/or the corrected index of pulse wave augmentation (AI × 80) ≥ -10% according to non-invasive arteriography data; and moderate-high cardiovascular risk (≥ 3%). Patients received therapy with lisinopril and simvastatin. Blood pressure (BP) levels and lipid profiles were assessed before therapy and in 1, 2, 6 and 12 month of the observation. Non-invasive arteriography was performed before therapy and in 2, 6 and 12 months later.</p><p><strong>Results.</strong> BP target levels were reached within 1 month of treatment as well as improvement of lipid profile was reached within 2 months in majority of the patients. Reference PWV and AI were reached in 85,7% of patients within one year of treatment.</p><strong>Conclusion.</strong> Arterial stiffness parameters help to evaluate cardiovascular risk changes accurately as the results of treatment. |
| first_indexed | 2024-03-12T10:57:11Z |
| format | Article |
| id | doaj.art-0c29915dd5f64dc2960691c1620876a1 |
| institution | Directory Open Access Journal |
| issn | 1819-6446 2225-3653 |
| language | English |
| last_indexed | 2024-03-12T10:57:11Z |
| publishDate | 2016-01-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj.art-0c29915dd5f64dc2960691c1620876a12023-09-02T06:11:09ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532016-01-0153141810.1234/1819-6446-2009-3-14-18655ARTERIAL STIFFNESS PARAMETERS IN PATIENTS WITH MODERATE/HIGH CARDIOVASCULAR RISK DURING LISINOPRIL AND SIMVASTATIN TREATMENTV. N. Isakova0O. G. Garbuzova1E. V. Klinkova2E. V. Bandurko3Медицинский центр «Прима Медика», Дальневосточный государственный медицинский университетМедицинский центр «Прима Медика», Дальневосточный государственный медицинский университетМедицинский центр «Прима Медика»Медицинский центр «Прима Медика»<p><strong>Aim.</strong> To evaluate parameters of arterial stiffness by non-invasive arteriography in patients with moderate/high cardiovascular risk receiving lisinopril and simvastatin.</p><p><strong>Material and methods.</strong> 20 patients (aged 50-55 y.o.) with arterial hypertension of the 1st degree and dislipidemia are included in the study. All patients had pulse wave velocity (PWV) ≥ 10 m/s and/or the corrected index of pulse wave augmentation (AI × 80) ≥ -10% according to non-invasive arteriography data; and moderate-high cardiovascular risk (≥ 3%). Patients received therapy with lisinopril and simvastatin. Blood pressure (BP) levels and lipid profiles were assessed before therapy and in 1, 2, 6 and 12 month of the observation. Non-invasive arteriography was performed before therapy and in 2, 6 and 12 months later.</p><p><strong>Results.</strong> BP target levels were reached within 1 month of treatment as well as improvement of lipid profile was reached within 2 months in majority of the patients. Reference PWV and AI were reached in 85,7% of patients within one year of treatment.</p><strong>Conclusion.</strong> Arterial stiffness parameters help to evaluate cardiovascular risk changes accurately as the results of treatment.http://www.rpcardio.ru/jour/article/view/656неинвазивная артериографияскорость пульсовой волнылизиноприлсимвастатин |
| spellingShingle | V. N. Isakova O. G. Garbuzova E. V. Klinkova E. V. Bandurko ARTERIAL STIFFNESS PARAMETERS IN PATIENTS WITH MODERATE/HIGH CARDIOVASCULAR RISK DURING LISINOPRIL AND SIMVASTATIN TREATMENT Рациональная фармакотерапия в кардиологии неинвазивная артериография скорость пульсовой волны лизиноприл симвастатин |
| title | ARTERIAL STIFFNESS PARAMETERS IN PATIENTS WITH MODERATE/HIGH CARDIOVASCULAR RISK DURING LISINOPRIL AND SIMVASTATIN TREATMENT |
| title_full | ARTERIAL STIFFNESS PARAMETERS IN PATIENTS WITH MODERATE/HIGH CARDIOVASCULAR RISK DURING LISINOPRIL AND SIMVASTATIN TREATMENT |
| title_fullStr | ARTERIAL STIFFNESS PARAMETERS IN PATIENTS WITH MODERATE/HIGH CARDIOVASCULAR RISK DURING LISINOPRIL AND SIMVASTATIN TREATMENT |
| title_full_unstemmed | ARTERIAL STIFFNESS PARAMETERS IN PATIENTS WITH MODERATE/HIGH CARDIOVASCULAR RISK DURING LISINOPRIL AND SIMVASTATIN TREATMENT |
| title_short | ARTERIAL STIFFNESS PARAMETERS IN PATIENTS WITH MODERATE/HIGH CARDIOVASCULAR RISK DURING LISINOPRIL AND SIMVASTATIN TREATMENT |
| title_sort | arterial stiffness parameters in patients with moderate high cardiovascular risk during lisinopril and simvastatin treatment |
| topic | неинвазивная артериография скорость пульсовой волны лизиноприл симвастатин |
| url | http://www.rpcardio.ru/jour/article/view/656 |
| work_keys_str_mv | AT vnisakova arterialstiffnessparametersinpatientswithmoderatehighcardiovascularriskduringlisinoprilandsimvastatintreatment AT oggarbuzova arterialstiffnessparametersinpatientswithmoderatehighcardiovascularriskduringlisinoprilandsimvastatintreatment AT evklinkova arterialstiffnessparametersinpatientswithmoderatehighcardiovascularriskduringlisinoprilandsimvastatintreatment AT evbandurko arterialstiffnessparametersinpatientswithmoderatehighcardiovascularriskduringlisinoprilandsimvastatintreatment |