Scalable, Robust and Highly Productive Novel Convecdiff Membrane Platform for mAb Capture
The recombinant monoclonal antibody capture step represents the current bottleneck in downstream processing. Protein A resins are diffusion-limited chromatography materials which require low flow rates to achieve a binding capacity above 30 g L<sup>−1</sup> with the result of low product...
Main Authors: | Mario Grünberg, Kim B. Kuchemüller, Katrin Töppner, Ricarda A. Busse |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-06-01
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Series: | Membranes |
Subjects: | |
Online Access: | https://www.mdpi.com/2077-0375/12/7/677 |
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