Knocking out central metabolism genes to identify new targets and alternating substrates to improve lipid synthesis in Y. lipolytica

Knocking out central metabolism genes to identify new targets and alternating substrates to improve lipid synthesis in Y. lipolytica

Introduction: Systematic gene knockout studies may offer us novel insights on cell metabolism and physiology. Specifically, the lipid accumulation mechanism at the molecular or cellular level is yet to be determined in the oleaginous yeast Y. lipolytica.Methods: Herein, we established ten engineered...

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Bibliographic Details
Main Authors:	Jiang Zhu, Yang Gu, Yijing Yan, Jingbo Ma, Xiaoman Sun, Peng Xu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Series:	Frontiers in Bioengineering and Biotechnology
Subjects:	Yarrowia lipolytica lipogenesis central metabolism lipid synthesis metabolic engineering
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2023.1098116/full

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